Thrombotic complications in von Willebrand disease |
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Authors: | Massimo Franchini |
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Institution: | Servizio di Immunoematologia e Trasfusione, Azienda Ospedaliera di Verona, Verona, Italy |
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Abstract: | Thrombotic events occur rarely in patients with von Willebrand disease (VWD). In this review we analyze the data reported in the literature, selected through a PubMed search, on thrombotic complications in VWD patients. On the basis of this analysis, we conclude that thrombotic complications in VWD patients often have a multi-factorial pathogenesis resulting from a complex interaction between acquired (coagulation factor replacement, surgery, cardiovascular risk factors) and/or inherited (thrombophilic gene mutations) prothrombotic risk factors. |
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Keywords: | VON WILLEBRAND DISEASE THROMBOSIS FACTOR CONCENTRATE THROMBOTIC RISK FACTORS |
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