| RP—HPLC测定骨炎灵颗粒中阿魏酸的含量 |
| |
| 引用本文： | 付泽华.RP—HPLC测定骨炎灵颗粒中阿魏酸的含量[J].中国中医药咨讯,2011,3(19):7-8. |
| |
| 作者姓名： | 付泽华 |
| |
| 作者单位： | 四川省巴中食品药品检验所,四川,巴中,636000 |
| |
| 摘 要： | 目的建立骨炎灵颗粒中阿魏酸的含量测定方法。方法采用RH—HPLC法，十八烷基硅烷键合相色谱柱；流动相为甲醇-乙腈-1．0％冰醋酸溶液（24：4：72）；检测波长322nm。结果阿魏酸在0．073～2．92μg范围内与峰面积呈很好的线性关系，平均回收率为98．06％，RSD=1．23％（n=6）。结论所建方法结果准确、操作简便，能用于控制骨炎灵颗粒的质量。
|
| 关 键 词： | 骨炎灵颗粒 阿魏酸 高效液相色谱法 |
Determination of fernlaic acid in Guyanling Granule by RP-HPLC |
| |
| Fu Ze-hua.Determination of fernlaic acid in Guyanling Granule by RP-HPLC[J].Journal of China Traditional Chinese Medicine Information,2011,3(19):7-8. |
| |
| Authors: | Fu Ze-hua |
| |
| Institution: | Fu Ze-hua Bazhong Insititute for Drug Control,Bazhong 636000 |
| |
| Abstract: | Objective To establish a method to determine ferulaic acid in Guyanling Granule. Methods A RP-HPLC method was adopted with C18 column（4.6 mmx 150 ram,5 tx m）. The mobile phase was consisted of methanol-acetonitrile-1.0% acetic acid （24±72）, detection wavelength was set at 322 nm. Results The calibration curve showed a good linearity within the range of 0.073± 2.92μg, r=-0.9999. The average recovery was 98.06% with RSD of 1.23%（n=6）. Conclusion The method is accurate, simple and reliable for the ~ualitv control of Guvanling Granule. |
| |
| Keywords: | Guyanling Granule Ferulaic acid HPLC |
| 本文献已被 维普 万方数据 等数据库收录！ |
