胃轻瘫犬固体胃排空特征的超声评价

目的 探讨清醒状态下胃轻瘫比格犬的固体胃排空特征。方法 采用双侧迷走神经干切断术联合胰高血糖素复制胃轻瘫犬动物模型，运用超声成像技术评价比格犬正常和胃轻瘫状态下固体胃排空功能，并与核素SPECT闪烁成像结果进行比较。结果 比格犬的固体胃排空过程符合改良的指数模型：Y=1-(1-e-k1)β，胃轻瘫比格犬的胃半排时间较正常显著延长，差异具有统计学意义(P＜0.05)。结论 胃轻瘫比格犬的固体胃排空特征具有稳定的数学表达方式。

Evaluate the solid gastric emptying characteristics of gastroparesis canine with ultrasound

Objective To explore the solid gastric emptying characteristics of awake gastroparesis Beagle. Methods A Beagle model of gastroparesis was established by truncal vagotomy combined injection glucagon. Solid gastric emptying of the Beagle under normal and gastroparesis were evaluated with ultrasound imaging,and compared with the results of radionuclide SPECT scintigraphy. Results The solid gastric emptying process of the Beagle was in accordance with modified power exponential models: Y =1-(1-e-kt)β, half time of the gastric emptying of gastroparesis Beagle was obviously longer than normal, there was a significant difference between the two situation ( P ＜ 0.05). Conclusions The solid gastric emptying characteristics of the gastroparesis Beagle has a stable mathematical expression.