| 成骨细胞在生物活性材料中黏附性能研究进展 |
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| 引用本文： | 牛旭锋,罗彦凤,潘君,王远亮. 成骨细胞在生物活性材料中黏附性能研究进展[J]. 生物医学工程学杂志, 2005, 22(4): 848-852 |
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| 作者姓名： | 牛旭锋 罗彦凤 潘君 王远亮 |
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| 作者单位： | 重庆大学,生物工程学院,生物力学与组织工程教育部重点实验室,重庆,400044 |
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| 基金项目： | 国家自然科学基金资助项目(30270395,30300084)，国家“863”计划资助项目(2003AA32X210) |
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| 摘 要： | 成骨细胞与骨基质材料间的相互作用是骨组织工程研究的主要领域,其中细胞与材料的黏附是基础,细胞必须与材料发生适当的黏附,才能进行迁移、增殖和分化。综述了与成骨细胞黏附有关的蛋白质、生物活性复合材料的表面特征和表面修饰对成骨细胞黏附性能的影响,为骨组织工程的研究提供一定的依据,尤其为组织工程新材料的研制提供参考。
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| 关 键 词： | 成骨细胞 生物活性材料 黏附性能 |
| 收稿时间： | 2003-10-20 |
| 修稿时间： | 2003-10-202004-01-16 |
Advance in Research of Osteoblast Adhesion to Bioactive Materials |
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| Niu Xufeng,Luo Yanfeng,Pan Jun,Wang Yuanliang. Advance in Research of Osteoblast Adhesion to Bioactive Materials[J]. Journal of biomedical engineering, 2005, 22(4): 848-852 |
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| Authors: | Niu Xufeng Luo Yanfeng Pan Jun Wang Yuanliang |
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| Affiliation: | Key Lab of Biomechanics & Tissue Engineering (Chongqing University) under Ministry of Education, Bioengineering College of Chongqing University, Chongqing, China. |
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| Abstract: | In the research field of bone tissue engineering,the interaction of osteoblast and substrate is pivotal and the adhesion of osteoblast to biomaterials is the basic condition. Firstly, osteoblast must adhere to biomaterials, then it can migrate, proliferate and differentiate. This paper introduces the proteins relating to the adhesion of osteoblast and the influences of relating surface character and modification of biomaterials on the adhesion ability of osteoblast. These could serve as basic data and useful reference for the development of bone tissue engineering and tissue engineering scaffold materials. |
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| Keywords: | Osteoblast Bioactive materials Adhesion ability |
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