稳定性二氧化氯含漱液治疗牙龈炎的临床研究

目的　验证稳定性二氧化氯含漱液 (口腔爽含漱液 )治疗牙龈炎的临床效果。方法　采用双盲临床对照试验方法 ,选择 10 0名患有牙龈炎的 17～ 2 0岁的男女学生作为研究对象 ,随机分成两组 ,每组 5 0人 ,男女均等。试验组给以口腔爽含漱液 ,对照组给以口泰含漱液 ,观察两组受试者使用含漱液 7d前后的牙龈指数和菌斑指数的变化 ,依此来评价口腔爽含漱液的临床效果。结果　使用口腔爽含漱液受试者的平均牙龈指数和菌斑指数分别减少0 .6 6和 0 .91,均有统计学显著性意义 (P <0 .0 0 1) ;与对照组分别为 0 .6 4、1.0 6比较 ,差异无显著性意义 (P >0 .5 0 )。结论　口腔爽含漱液对治疗牙龈炎、控制牙菌斑有明显效果 ,与口泰无显著差别 ,且口感好 ,未发现任何副作用 ,是一种新型的口腔含漱液 ,值得在临床上推广应用。

A Study of Clinical Therapeutic Efficacy of Stability ClO2 Gargle in the Treatment of Gingivitis

Objective To prove the clinical therapeutic efficacy of stability ClO 2 gargle (Kouqiangshuang gargle) in the treatment of gingivitis. Methods In this double blind clinical trial, one hundred healthy male and female students of 17-20 years old with gingivitis were divided into two groups at random. As a topical medication, Kouqiangshuang gargle was applied to the students of experimental group and Koutai was applied to the control group. After seven days, the gingival index and plaque index were recorded. Results The average gingival index and plaque index statistically significantly(P<0.001) reduced 0.66 and 0.91 in the experimental group respectively, while there was no significant difference when compared with the control group of 0.64, 1.06(P>0.50) respectively. Conclusion There were obvious efficacy that kouqiangshuang gargle treated gingivitis, controled dental plaque, no difference compared with koutai gargle. Kouqiangshuang gargle had a good taste, no any side effects in the clinical test. Therefore it is a new gargle, and deserves to be expansively applied clinically.