Axonal transport in the central axon of sensory neurons during regeneration of their peripheral axon |
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Authors: | M A Bisby |
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Affiliation: | Division of Medical Physiology, The University of Calgary, Calgary, Alberta T2N 1N4 Canada |
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Abstract: | Following sciatic nerve injury (which provokes prompt regeneration of peripheral sensory axons) there was no change in the ratio between amounts of labeled protein conveyed by fast axonal transport into the central and peripheral axons. A change in composition of the transported protein, characteristic of regenerating peripheral axons, also occurred in the central axons. When the peripheral axon is injured, changes in axonal transport thus affect both processes, and there is no routing of fast-transported protein into or away from the regenerating process. |
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Keywords: | To whom correspondence should be addressed at: Neuroscience Research Laboratory Medical Research Service (151) VA Medical Center 4801 Linwood Blvd. Kansas City MO 64128 U.S.A. |
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