双胎妊娠并发重度子痫前期母儿结局分析

目的:探讨双胎妊娠并发重度子痫前期的母儿结局。方法:回顾总结湖州市妇幼保健院2005年1月~2007年12月收治的66例双胎妊娠和451例单胎妊娠并发重度子痫前期孕妇的妊娠结局,以单、双胎分两组比较其发病情况、母儿并发症及结局。结果:双胎妊娠比单胎妊娠发病孕周早、期待治疗时间短(P<0.05)、早产和产后出血发生率高(P<0.01);两组孕妇并发子痫、胎盘早剥、HELLP综合征及围产儿死亡率比较,差异无统计学意义(P>0.05);双胎妊娠胎龄不同对围生儿结局会产生不同的影响。结论:双胎妊娠孕妇须注重孕期保健,减少重度子痫前期的发生;对发生重度子痫前期者应积极控制病情、延长孕周、减少低龄早产儿出生;胎龄36周终止妊娠围生儿结局最好。

Analysis on pregnant outcomes of twin pregnancy combined with severe preeclampsia

To explore the pregnant outcomes of twin pregnancy complicated with severe preeclampsia. Methods: The pregnant outcomes of 66 twin pregnancies complicated with severe preeclampsia and 451 singleton pregnancies complicated with severe pre-eclampsia were analysed retrospectively and compared from January 2005 to December 2007. Results: The disease time and the time of ex-pectant treatment in twin pregnancy group were shorter than those in singleton pregnancy group (P<0. 05) . The incidences of premature delivery and postpartum hemorrhage in twin pregnancy group were significantly higher than those in singleton pregnancy group (P<0. 01) There was no difference in the incidences of eclampsia, placental abruption, HELLP syndrome and prenatal mortality (P>0. 05) . There was correlation between pregnant weeks of twin pregnancy and prenatal outcomes. Conclusion: Women of twin pregnancy are required to no-tice more about health care in order to decrease the incidence of severe preeclampsia. As to the affected, the measures such as controlling the development and prolonging the gestational age should be carried out to decrease the incidence of premature delivery. It is advisable to termi-nate pregnancy on the 36th pregnant weeks.