恙虫病并发中毒性肝炎40例临床分析

目的探讨恙虫病并发中毒性肝炎的临床特点。方法按诊断标准选择病例进行临床分析。结果本组除了具有恙虫病特征性的临床表现外，同时出现黄疸占25％(总胆红素平均164μmol/L)，出血点和瘀斑占15％，肝大占76％，脾大占63％。ALT和AST升高，平均分别为295U/L和240U/L。使用特效抗茵药物和护肝退黄治疗有良效。结论恙虫病并发中毒性肝炎较常见，少数可出现严重的肝功能损害。

A clincal study on scrub typhus with the complication of toxic hepatitis in 40 patients

Objective To study the clinical features of scrub typhus with the complication of toxic hepatitis.Methods Patients accorded with diagnostic standards were selected and analysed.Results Jaundice(25%),petechiae or ecchymoses(15%),hepatomegaly(76%),splenomegaly(63%) elevated alanine transaminase(average 295IU/L) and aspartate transaminase(average 240IU/L) were seen in these patients besides ordinary clinical manifestations of scrub typhus.Pathogenic and symptomatic treatments were effective.Conclusion Toxic hepatitis is quite often seen in patients with scrub typhus,and may result in severe lesion of liver functions in some of them.