多烯磷脂酰胆碱治疗药物性肝炎96例临床疗效分析

目的：探讨多烯磷脂酰胆碱治疗药物性肝炎的临床疗效分析。方法对本院2013年8月至2014年10月收治的96例药物性肝炎患者进行治疗，将96例患者随机分成两组，对照组采用常规保肝抗炎方法治疗，观察组采用常规方法外加用多烯磷脂酰胆碱治疗，观察两组效果并比较。结果对照组总有效率83．33％不及观察组93．75％，观察组各项肝功能指标改善情况优于对照组，两组比较均存在差异明显，P＜0．05，差异具有统计学意义。结论多烯磷脂酰胆碱治疗药物性肝炎的临床疗效良好，能够显著改善患者肝功能指标，同时提高治疗的有效率，因而值得临床使用。

Clinical Therapy Efficacy of Polyunsaturated Phosphatidylcholine (PPC)from 96 Patients with Drug-Induced Hepatitis

Objective To analyze the clinical therapy efficacy of Polyunsaturated phosphatidylcholine (PPC) from 96 cases with drug-induced hepatitits .Methods Total of 96 patients with drug-induced hepatitis (from 08/2013 to 10/2014) were enrolled and randomly divided into the control group and the treatment group .Patients in control group were treated with the routine treatment of hepatic protection and anti-inflammatory ,while patients in treatment group were treated with PPC and routine treatment .Com-pare the efficacy of two groups .Results The total effective rates of the two groups (treatment group 93 .75% vs control group 83 . 33% ) showed significant difference (P<0 .05) .Serum T-BIL ,ALT and AST levels in treatment group were lower than the control group after therapy .Conclusion PPC treatment is effective for drug-induced hepatitis and it improves the clinical symptoms and signs .It is worthy for clinical use .