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寻常性银屑病患者外周血神经节苷酯GD1b检测及意义
引用本文:李立红,董萍云,刘晓松. 寻常性银屑病患者外周血神经节苷酯GD1b检测及意义[J]. 中国皮肤性病学杂志, 2008, 22(1): 30-31
作者姓名:李立红  董萍云  刘晓松
作者单位:河北医科大学第二医院,河北,石家庄,056000
摘    要:
目的探讨神经节苷酯GD1b在寻常性银屑病发病中的作用。方法采用ELISA法检测寻常性银屑病组和对照组血清GD1b浓度。结果银屑病组血清GD1b为45.737±16.2556EU/mL,明显高于对照组(P<0.05)。结论神经节苷酯GD1b可能通过调节角质形成细胞的增生参与银屑病的发病。

关 键 词:银屑病  神经节苷酯
文章编号:1001-7089(2008)01-0030-01
收稿时间:2007-06-26
修稿时间:2007-07-26

Expression and Significance of GD1 b in Peripheral Blood in Psoriasis Vulgaris Patients
LI Li-hong,DONG Ping-yun,LIU Xiao-song. Expression and Significance of GD1 b in Peripheral Blood in Psoriasis Vulgaris Patients[J]. The Chinese Journal of Dermatovenereology, 2008, 22(1): 30-31
Authors:LI Li-hong  DONG Ping-yun  LIU Xiao-song
Abstract:
Objective To investigate gangliosideGD1b in the pathogenesis of psoriasis.Methods gangliosideGD1b serum concentration of patients with psoriasis vulgaris and healthy controls were detected by ELISA method.Results The levels of GD1b in the serum of psoriasis vulgaris patients were significantly higher than that of control subjects(P<0.05).Conclusion GD1b may participate the invasion of the psoriasis,through regulating the proliferation of keratinocyte.
Keywords:Psoriasis  Ganglioside
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