| 西酞普兰和阿米替林治疗老年抑郁症效果比较 |
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| 引用本文： | 王东明,崔维珍,孙波. 西酞普兰和阿米替林治疗老年抑郁症效果比较[J]. 齐鲁医学杂志, 2006, 21(4): 296-297 |
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| 作者姓名： | 王东明 崔维珍 孙波 |
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| 作者单位： | 青岛市精神卫生中心,山东,青岛,266034;青岛市精神卫生中心,山东,青岛,266034;青岛市精神卫生中心,山东,青岛,266034 |
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| 摘 要： | 目的比较西酞普兰与阿米替林治疗老年抑郁症的疗效及不良反应。方法将72例符合CCMD-3诊断标准的老年抑郁症病人随机分为两组,分别采用西酞普兰和阿米替林治疗8周,采用汉密尔顿抑郁量表(HAMD)、汉密尔顿焦虑量表(HAMA)和副反应量表(TESS)评定疗效和不良反应。结果西酞普兰组疗效优于阿米替林组(uc=1.81,P<0.05),副作用轻于阿米替林组(t=5.01~15.91,P<0.05、0.01)。结论西酞普兰是一种既有效又安全的新型抗抑郁药,适用于老年抑郁症的治疗。
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| 关 键 词： | 西酞普兰 阿米替林 抑郁症 老年人 治疗结果 |
| 文章编号： | 1008-0341(2006)04-0296-02 |
| 收稿时间： | 2005-06-22 |
| 修稿时间： | 2006-05-22 |
COMPARISON BETWEEN THE THERAPEUTIC EFFECTS OF CITALOPRAM AND AMITRIPTYLINE FOR SENILE DEPRESSION |
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| WANG DONG-MING,CUI WEI-ZHEN,SUN BO. COMPARISON BETWEEN THE THERAPEUTIC EFFECTS OF CITALOPRAM AND AMITRIPTYLINE FOR SENILE DEPRESSION[J]. Medical Journal of Qilu, 2006, 21(4): 296-297 |
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| Authors: | WANG DONG-MING CUI WEI-ZHEN SUN BO |
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| Affiliation: | The Mental Health Center of Qingdao, Qingdao 266034, China |
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| Abstract: | ObjectiveTo compare the therapeutic effects and side effects of citalopram and amitriptyline in the treatment of senile depression.MethodsSeventy-two patients confirmed to CCMD-3 standards were randomized evenly to citalopram group and amitriptyline group.They were given citalopram or amitriptyline for eight weeks.The therapeutic effects and side effects were evaluated by HAMD,HAMA and TESS.ResultsCitalopram showed better therapeutic effects(u_c =1.81,P<0.05) and less side effects than amitriptyline(t=5.01-15.91;P<0.05,0.01).ConclusionCitalopram is an effective and safe antidepressant in the treatment of the aged depression. |
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| Keywords: | citalopram amitriptyline depression aged treatment outcome |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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