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| 肝癌患者纤维蛋白原和D-二聚体的检测结果分析 | |
| 引用本文： | 钮心怡,周盛杰,陈泽英. 肝癌患者纤维蛋白原和D-二聚体的检测结果分析[J]. 分子诊断与治疗杂志, 2009, 1(2): 108-110 |
| 作者姓名： | 钮心怡 周盛杰 陈泽英 |
| 作者单位： | 1. 广东省第二中医院检验科,广东,广州,510095 2. 中山大学肿瘤防治中心,广东,广州,510060 |
| 摘 要： | 目的对肝癌患者的纤维蛋白原(Fib)和D-二聚体(D-dimer)进行检测,了解纤维蛋白原和D-二聚体与肝癌转移的关系,并评价其在肝癌辅助诊断的临床意义。方法取200例肝癌患者、30例对照组(健康体检者)的静脉血,采用乳胶凝集半定量法测定血浆D-dimer,采用全自动血凝仪检测Fib含量。结果200例肝癌患者中,肿瘤初治组和难治转移组的血浆D-dimer及Fib含量明显升高,治疗缓解组血浆D-dimer及Fib含量有不同程度下降。结论Fib及D-dimer含量的变化,与肝癌病情严重程度及预后显著相关。其检测方法简便、快速、敏感性高,可作为肝癌的辅助诊断及预后判断的一项早期诊断参考指标。 |
| 关 键 词： | 肝癌 纤维蛋白原 D-二聚体 预后 |
Study on the results from plasma fibrinogen and D-dimer in hepatocellular carcinoma |
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| NIU Xinyi,ZHOU Shengjie,CHEN Zeying. Study on the results from plasma fibrinogen and D-dimer in hepatocellular carcinoma[J]. Journal of Molecular Diagnosis and Therapy, 2009, 1(2): 108-110 | |
| Authors: | NIU Xinyi ZHOU Shengjie CHEN Zeying |
| Affiliation: | 1.Department of clinical laboratory, second traditional Chinese medicine hospital of Guangdong province, Guangdong, Guangzhou 510095, China; 2.Cancer Center, Sun Yat-sen University, Guangdong, Guangzhou 510060, China) |
| Abstract: | Objective To observe the relevance of plasma D-dimer and fibrinogen in hepatocellular carcinoma. Methods From 200 hcpatocellular carcinoma patients and 30 normal adults, plasma D-dimer levels and fibrinogen levels were measurad by Latex Agglutinative test(LAT), and semiautomatic coagulometer, respectively. Results Plasma D-dimer and fibrinogen levels in the primary therapy group were higher than that in the normal adults group, however they showed downtrend in the catabatic group. Conclusion Measure plasma D-dimer and fibrinogen levels could be a predictor in tumor patient. |
| Keywords: | Hepatocellular carcinoma Fibrinogen D-dimer Prognosis |
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