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Polymers for controlled parenteral delivery of peptides and proteins |
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| Authors: | Jorge Heller |
| Affiliation: | Controlled Release and Biomedical Polymers Department, SRI International Menlo Park, CA, USA |
| Abstract: | This review summarizes the current state of parenteral delivery of proteins and peptides. Although an attempt has been made to provide a comprehensive review, the more recent developments, such as delivery of LHRH analogues, vaccine delivery systems and regulated systems, have been emphasized. Non-regulated delivery systems have been divided into non-degradable and degradable and each has been subdivided into hydrophilic and hydrophobic systems. Regulated systems have been divided into externally regulated and self-regulated. |
| Keywords: | Protein release Bioerodible hydrogels Bioerodible polymer Lactide/glycolide co-polymers Polyanhydrides Poly(ortho esters) Vaccines Regulated drug delivery |
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