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枸杞子及其有效成分的药理作用研究进展
引用本文:张敏,岳坤,姜交华,陈海佳. 枸杞子及其有效成分的药理作用研究进展[J]. 现代药物与临床, 2023, 46(7): 1611-1619
作者姓名:张敏  岳坤  姜交华  陈海佳
作者单位:广东省赛莱拉干细胞研究院, 广东 广州 510000;广东省赛莱拉干细胞研究院, 广东 广州 510000;广州赛莱拉干细胞科技股份有限公司, 广东 广州 510000
基金项目:广州市科技人才专项基金项目(201909020006);广州开发区领军人才项目(2020-L035)
摘    要:枸杞子Lycium barbarum是食药同源中药材,具有滋阴兴阳、止消渴、补劳伤的功效,富含枸杞多糖、枸杞总黄酮、类胡萝卜素和氨基酸等多种有效成分。现代药理学的研究显示,枸杞子及其活性成分具有抗肿瘤、调节血糖血脂、保护视力、抗抑郁与焦虑、防治神经系统疾病、抗炎抑菌、抗氧化、保护肝肺肾等作用。对枸杞子及其有效成分的药理作用进行总结和归纳,以期为其进一步应用开发及新药研究提供依据。

关 键 词:枸杞子  枸杞多糖  枸杞总黄酮  抗肿瘤  调节血糖  抗氧化
收稿时间:2022-12-26

Research progress on pharmacological effects of Lycii Fructus and its active ingredients
ZHANG Min,YUE Kun,JIANG Jiaohu,CHEN Haijia. Research progress on pharmacological effects of Lycii Fructus and its active ingredients[J]. Drugs & Clinic, 2023, 46(7): 1611-1619
Authors:ZHANG Min  YUE Kun  JIANG Jiaohu  CHEN Haijia
Affiliation:Saliai Stem Cell Institute of Guangdong, Guangzhou 510000, China; Saliai Stem Cell Institute of Guangdong, Guangzhou 510000, China;Guangzhou Saliai Stem Cell Science and Techonology Co., Ltd., Guangzhou 510000, China
Abstract:Lycii Fructus is a traditional Chinese medicine that can be used for both food and medicine. It has the effects of nourishing yin and promoting yang, stopping thirst, and especially tonifying labor injuries. It is rich in Lycium barbarum polysaccharides, total flavonoids of Lycium barbarum, carotenoids, amino acids and other active ingredients. Studies have shown that Lycii Fructus and its active ingredients have the functions of anti-tumor, regulating blood glucose and blood lipids, protecting visual function, anti-depression and anxiety, preventing and treating nervous system diseases, anti-inflammatory and bacteriostasis, anti-oxidation, protecting liver, lung and kidney. This article summarizes the pharmacological effects of the effective components of Lycii Fructus, providing a basis for further application development and new drug research.
Keywords:Lycium barbarum L.  Lycium barbarum polysaccharides  total flavonoids of Lycium barbarum  anti-tumor  regulating blood sugar  anti-oxidation
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