女性膀胱颈硬化症两种治疗方法前后尿动力学的变化

目的:通过对女性膀胱颈硬化症进行手术及尿道扩张两种治疗方法尿动力学的比较,期望发现影响治疗效果的原因。方法:尿道扩张组30例,手术治疗(TUR-BN)组30例,每例患者均进行6次尿动力学检查,即治疗前、治疗结束后1个月、2个月、3个月、6个月、1年。结果:尿道扩张组有效率30%,无效率70%。手术治疗组有效率90%,无效率10%。治疗有效患者的尿动力学参数最大尿流率增大、平均尿流率增大、残余尿量减少、最大逼尿肌压降低。术后仍有排尿梗阻症状患者的尿动力学参数最大尿流率、平均尿流率、残余尿量、最大逼尿肌收缩压与术前无差异。结论:经尿道膀胱颈切开术是治疗女性膀胱颈硬化症的有效方法,优于尿道扩张治疗。

Effect of transurethral resection on urodynamics in the treatment of female bladder neck sclerosis

Objectives： To explore the effect of transurethral resection of bladder neck（TUR-BN） on urodynamics in the treatment of female bladder neck sclerosis.Method： Expectant treatment （urethral sounding） were conducted on 30 patients with urethral dilatation and on 30 cases with TUR-BN for 6 times in total,namely,in the first month,second month,third month,sixth month and one year after the treatment.Results： In the urethral dilatation group,the effective rate was 30％ ; the ineffective rate was 70％.In the TUR-BN group,the effective rate was 90％ ; the ineffective rate was 10％.Of the effective cases in the TUR-BN group,the urodynamic parameter of Qmax and Qave increased; the residual urine volume and maximum pressure of detrusor contraction decreased,while the indicators showed no difference in invalid cases.Conclusion： TUR-BN proves to be more effective in the treatment of female bladder neck sclerosis as compared with the urethral dilation treatment.