α - 干扰素栓联合微波治疗人乳头瘤病毒感染宫颈糜烂的疗效观察

目的：分析α-干扰素栓联合微波治疗HPV感染宫颈糜烂的临床疗效。方法：选取2012年7月至2013年7月期间于我院妇科门诊实施治疗的HPV感染宫颈糜烂患者90例，按照就诊顺序将其随机分为研究组与参照组两组。其中研究组（45例）采用α-干扰素栓与微波配合治疗，参照组（45例）仅采用微波治疗，对比两组的临床治疗效果。结果：研究组的治疗有效率明显高于参照组（93.33％ VS 75.56％），半年、1年复发率明显低于参照组（4.65％ VS 15.56％，9.30％ VS 24.44％），P＜0.05；另讲师外，在研究组不同病变程度治疗总有效率上，中度糜烂型明显高于重度糜烂型（96.00％ VS 77.78％），P＜0.05，有统计学意义。结论：α-干扰素栓配合微波治疗HPV感染宫颈糜烂，操作简便，治疗效果显著，副反应少，反复发病率低，安全可靠，值得临床广泛应用。

Curative effect of alpha interferon suppository combining microwave in treating human papillama virus in-fected cervical erosion

Objectives：To analyze the clinical effects of alpha interferon suppository combining microwave in the treatment of human papillama virus （HPV）infected cervical erosion.Methods：90 patients with HPV infec-ted cervical erosion that received outpatient treatment in the Department of Gynaecology in our hospital from July 2012 to July 2013 were selected and randomly divided into research group and control group according to visiting or-der.The research group （45 cases）adopted alpha interferon suppository combining microwave therapy,while con-trol group （45 cases）only adopted microwave treatment.Clinical therapeutic effects of the two groups were com-pared.Results：The treatment effect of research group was obviously higher than control group （93.33% VS 75.56%）,while its recurrence rates half a year and one year later were significantly lower than these of control group （4.65%VS 15.56%,9.30%VS 24.44%）,P〈0.05;In addition,of the total effective rate at different degree of pathological changes in the research group,moderate erosion type was significantly higher than severe erosion type （96.00%VS 77.78%）,P〈0.05,with statistical significance.Conclusions：Alpha interferon suppository combi-ning microwave in the treatment of HPV infected cervical erosion is easy,safe and reliable,with outstanding treatment effect,less side effect and low recurrence rate,which is worth wide application in clinical practice.