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Small bowel non-Hodgkin's lymphoma remaining in complete remission by surgical resection and adjuvant rituximab therapy |
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| Authors: | Nomura Kenichi Tomikashi Koichi Matsumoto Yosuke Yoshida Naohisa Okuda Takashi Sakakura Chohei Mitsufuji Shoji Horiike Shigeo Yamagishi Hisakazu Okanoue Takeshi Taniwaki Masafumi |
| Affiliation: | 1. Molecular Hematology and Oncology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan 2. Molecular Gastroenterology and Hepatology, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan 3. Department of Surgery,Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan 4. Clinical Molecular Genetics and Laboratory Medicine, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan |
| Abstract: | A 44-year-old man was referred to our hospital with intermittent abdominal pain. Because distention of fluid- and gas-filled loops of small intestine was proved by X-ray, the patient was diagnosed as having small bowel obstruction. A laparotomy revealed a segmental stenosis in the jejunum, which showed diffuse thickening of the intestinal wall. Some mesenteric lymph nodes were swollen. Pathological examination was defined. We diagnosed diffuse large B-cell lymphoma based on the pathological findings of diffuse transmural infiltration of large lymphoid cells and flow-cytometric analyses. Rituximab was administered as adjuvant therapy at weekly doses of 375 mg/m2. Four cycles were performed every 6 mo and he remained CR. Rituximab may be effective as adjuvant therapy. |
| Keywords: | Intermittent abdominal pain Rituximab |
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