Case Report: Suspected Hyperacute Rejection During Living Kidney Transplantation |
| |
| Affiliation: | 1. Department of Urology and Transplant Surgery, Toda Chuo General Hospital, Saitama, Japan;2. Department of Urology, Tokyo Women''s Medical University, Tokyo, Japan;3. Department of Urology, Tokyo Women''s Medical University, Yachiyo Medical Center, Chiba, Japan;4. Department of Urology, Juntendo University Urayasu Hospital, Chiba, Japan;5. Department of Organ Transplant Medicine, Tokyo Women''s Medical University, Tokyo, Japan;1. Department of Gastroenterological Surgery 1, Graduate School of Medicine, Hokkaido University Sapporo, Sapporo, Japan;2. Gastroenterological Surgery 1, Hokkaido University Hospital, Sapporo, Japan;3. Department of Cell Physiology, Jikei University School of Medicine, Tokyo, Japan;4. Department of Transplant Surgery, Graduate School of Medicine, Hokkaido University Sapporo, Sapporo, Japan;5. Division of Organ Transplantation, Hokkaido University Hospital, Sapporo, Japan;1. Department of Transplantation and Regenerative Medicine, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan;2. Department of Endocrinology, Diabetes and Metabolism, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan;3. Department of Nephrology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan;1. Department of General Surgery, Dokuz Eylül University Hospital, Hepatobiliary Surgery and Liver Transplantation Unit, Izmir, Turkey;2. Department of Anesthesiology and Reanimation, Dokuz Eylül University Hospital, Izmir, Turkey;3. Department of Infectious Diseases, Dokuz Eylül University Hospital, Izmir, Turkey;4. Department of Gastroenterology, Dokuz Eylül University Hospital, Izmir, Turkey;5. Department of Pathology, Dokuz Eylül University Hospital, Izmir, Turkey;6. Department of General Surgery, Güven Hospital, Ankara, Turkey;7. Department of General Surgery, Memorial Bahçelievler Hospital, Istanbul, Turkey;1. Department of Surgery, Konkuk University School of Medicine, Seoul, South Korea;2. Department of Ophthalmology, Konkuk University Medical Center, Seoul, South Korea;3. Department of Pathology, Konkuk University School of Medicine, Seoul, South Korea;4. Department of Laboratory Medicine, Hallym University College of Medicine, Anyang-si, South Korea;5. Department of Thoracic and Cardiovascular Surgery, Konkuk University School of Medicine, Seoul, South Korea;6. Department of Cardiology, Konkuk University School of Medicine, Seoul, South Korea;7. Animal Biotechnology Division, National Institute of Animal Science, Wanju-gun, South Korea;8. Non-Human Primate Minipig Translational Toxicology Research, Korea Institute of Toxicology, Jeonbuk, Jeollabuk-do, South Korea;1. Department of Urology, Dokkyo Medical University Saitama Medical Center, Koshigaya-City, Saitama, Japan;2. Transplant Center, Dokkyo Medical University Saitama Medical Center, Koshigaya-City, Saitama, Japan;3. Division of Transplant Surgery, Tokyo Metropolitan Health and Hospitals Corporation Ohkubo Hospital, Shinjyuku-ku, Tokyo, Japan;4. Department of Nephrology, Dokkyo Medical University Saitama Medical Center, Koshigaya-City, Saitama, Japan |
| |
| Abstract: | BackgroundWe report a case of suspected hyperacute rejection during living kidney transplantation.Case reportA 61-year-old man underwent kidney transplantation in November 2019. Before the transplantation, immunologic tests revealed the presence of anti-HLA antibodies but not donor-specific HLA antibodies. The patient was intravenously administered 500 mg of methylprednisolone (MP) and basiliximab before perioperative blood flow reperfusion. After blood flow restoration, the transplanted kidney turned bright red and then blue. Hyperacute rejection was suspected. After the intravenous administration of 500 mg of MP and 30 g of intravenous immunoglobulin, the transplanted kidney gradually changed from blue to bright red. The initial postoperative urine output was good. On the 22nd day after the renal transplantation, the patient was discharged with a serum creatinine level of 2.38 mg/dL, and the function of the transplanted kidney gradually improved.ConclusionsIn this study, non-HLA antibodies may have been a cause of the hyperacute rejection, which was managed with additional perioperative therapies. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
