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不同年龄段健康儿童血清肌酸激酶同工酶(CK-MB)临床评估
引用本文:郑荣,董振南,董矜,郭广宏,温新宇. 不同年龄段健康儿童血清肌酸激酶同工酶(CK-MB)临床评估[J]. 军医进修学院学报, 2010, 31(4): 337-338,347
作者姓名:郑荣  董振南  董矜  郭广宏  温新宇
作者单位:解放军总医院,生化科,北京,100853
摘    要:
目的比较不同年龄段健康儿童血清肌酸激酶同工酶(CK-MB)活性和质量差异,并对其临床合理应用进行探讨。方法选取184例健康儿童,按年龄阶段进行分组,同时选取30例健康成人设为对照组,分别采用酶免疫抑制法测定血清CK-MB活性,双抗体夹心法测定血清CK-MB质量。结果各健康儿童组和成人组CK-MB活性和质量呈明显正相关;儿童组CK-MB活性和质量随年龄增长呈下降趋势,趋近成人水平;各组质量检测均在正常参考范围,而低年龄儿童组CK-MB活性略高于临床正常值。结论临床医生在参考CK-MB活性和质量检测结果进行病情判断时,要考虑年龄因素;在临床诊断中CK-MB质量测定更优于活性测定。

关 键 词:儿童  CK-MB  酶免疫抑制法  双抗体夹心法

Clinical evaluation of serum creatine phosphokinase isoenzyme in healthy children at different ages
ZHENG Rong,DONG Zhen-nan,DONG Jin,GUO Guang-hong,WEN Xin-yu. Clinical evaluation of serum creatine phosphokinase isoenzyme in healthy children at different ages[J]. Academic Journal of Pla Postgraduate Medical School, 2010, 31(4): 337-338,347
Authors:ZHENG Rong  DONG Zhen-nan  DONG Jin  GUO Guang-hong  WEN Xin-yu
Affiliation:ZHENG Rong,DONG Zhen-nan,DONG Jin,GUO Guang-hong,WEN Xin-yuDepartment of Clinical Biochemistry,Chinese PLA General Hospital,Beijing 100853,China
Abstract:
Objective To compare the different activity and quality of serum creatine phosphokinase isoenzyme (CK-MB) in healthy children at different ages and to study its rational clinical application. Methods A total of 184 healthy children were divided into different age groups and 30 healthy adults served as a control group. Activity and quality of their serum CK-MB were detected by inhibition enzyme immunoassay and double antibody sandwich enzyme-link immunoassay, respectively. Results A positive correlation was ...
Keywords:Child  CK-MB  Enzyme Inhibition Immunoassy  Double Antibody Sandwich Enzyme-Link Immunoassay  
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