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Fluosol and experimental spinal cord ischemia |
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| Authors: | S. Kolluri U. DeGirolami R. Heros F. Vacanti N. Zervas |
| Affiliation: | (1) Department of Surgery (Neurosurgery), Massachusetts General Hospital/Harvard Medical School, 02114 Boston, MA, USA;(2) Department of Anesthesiology, Massachusetts General Hospital/Harvard Medical School, 02114 Boston, MA, USA;(3) Department of Pathology (Neuropathology) and Neurology, University of Massachusetts Medical School, Boston, Massachusetts, USA |
| Abstract: | Summary Spinal cord ischemia was produced by temporary aortic occlusion for 12.5 min in 27 rabbits. Animals were divided into three groups: Group A received Fluosol DA 20% and 100% oxygen; Group B Fluosol and room air only, and Group C Dextran 40 and 100% oxygen. There was no difference in neurological outcome or in the extent and severity of histologically documented infarction of the spinal cord in the three groups. There was also no difference between these groups and untreated controls previously studied by us. |
| Keywords: | Ischemia Spinal cord Perfluorochemicals Dextran Hemodilution |
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