Functional inhibition of erectile process in rats by indomethacin

Objectives  

Despite the important role played by prostaglandins in the control of erection, the potential contribution of non-steroidal anti-inflammatory drugs in erectile dysfunction in experimental animals has not been investigated. We examined the effect of the selective COX-2 inhibitor, celexocib, and the non-selective COX-inhibitors, indomethacin and diclofenac on erectile process in vivo.