肿瘤 PICC 置管患者焦虑程度和生存质量的关系研究

目的：探讨影响PICC置管肿瘤患者焦虑发生的因素，并分析焦虑对患者生存质量的影响。方法选取2011年12月—2013年1月长期行静脉化疗的PICC置管肿瘤患者280例，根据焦虑自评量表（ SAS）评定患者的焦虑程度，分为焦虑患者和非焦虑患者，并收集患者一般资料，进行癌症患者生命质量测定量表（ EORTC QLQ-C30）调查，对调查结果进行分析。结果280例患者根据SAS评分，正常73例（26．07％）；焦虑总例数207例（73．93％），其中轻度焦虑41例（14．64％），中度焦虑106例（37．86％），重度焦虑60例（21．43％）。患者年龄、住院付费方式、文化程度、职业、月收入和治疗时间均可影响焦虑发生（χ2值分别为3．673，128．354，28．566，35．363，38．455，3．257；P＜0．05）。 EORTC QLQ-C30量表调查 PF、RF、DY 3个维度评分，焦虑患者分别为（58．6±21．3），（61．4±26．1），（41．6±28．9）分，非焦虑患者分别为（59．3±15．6），（64．1±22．7），（40．2±27．5）分，差异均无统计学意义（t值分别为－0．835，－1．256，0．248；P＞0．05）；EF、CF、SF、FA、NV、PN、QL、SL、AP、CO、DI、FI 12个维度评分差异均有统计学意义（ P＜0．05）。结论焦虑可影响EORTC QLQ-C30量表中的EF、CF、SF、FA、NV、PN、QL、SL、AP、CO、DI、FI 12个维度，改善患者的焦虑情况有助于提高PICC置管肿瘤患者的生存质量。

Relationship between anxiety degrees and dimensionalities of survival quality of cancer patients with PICC

Objective To explore the influence PICC catheter factors of anxiety in patients with tumor, and analyze the effect of anxiety on patients survival quality.Methods Between December 2011 and January 2013, 280 patients with PICC catheter tumors received long-term intravenous chemotherapy, according to the anxiety self rating scale （ SAS） to assess the degree of anxiety patients, were divided into anxiety patients and non-anxiety patients, then collected the patient ’ s general information, conducted cancer patients life scale （ EORTC QLQ C30 ） survey, analyzed the results.Results Among 280 patients, according to SAS scores, 73 cases of normal （26.07%）, 207 cases with anxiety （73.93%）, in which 41 cases of mild anxiety （14.64%）, 106 cases of moderate anxiety （37.86%）,60 cases of severe anxiety （21.43%）.The onset of patients age, hospitalization payment method, culture degree, occupation, income and treatment time had significantly relationship with the incidence of anxiety （χ2 =3.673,128.354,28.566,35.363,38.455,3.257, respectively;P〈0.05）.In EORTC QLQ C30-scale survey, anxiety and non-anxiety patients in PF （58.6 ± 21.3） vs （59.3 ±15.6）], RF（61.4 ±26.1） vs （64.1 ±22.7）], DY scores （41.6 ±28.9） vs （40.2 ± 27.5）] had no significant difference （t=-0.835,-1.256,0.248, respectively;P〉0.05）.And significant difference of 12 dimensions scores was found （ P〈0.05） .Conclusions Anxiety can affect 12 dimensions（ EF, CF, SF, FA, NV, PN, QL, SL, AP, CO, DI, FI ） of EORTC QLQ C30 scale, improving the patient’ s anxiety can help improve the quality of survival in patients with PICC catheter tumor.