| 双波长分光光度法测定牙周康的含量 |
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| 引用本文： | 杨永铁,刘迎春,王鸿钢,王国清,费夷敏.双波长分光光度法测定牙周康的含量[J].齐鲁药事,2005,24(1):26-27. |
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| 作者姓名： | 杨永铁 刘迎春 王鸿钢 王国清 费夷敏 |
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| 作者单位： | 1. 沈阳贝朗制药有限公司,沈阳,110026
2. 沈阳药科大学制药工程学院,沈阳,110016 |
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| 摘 要： | 目的 测定牙周康中甲硝唑和芬布芬的含量。方法 采用双波长分光光度法,甲硝唑以 314nm为测定波长,2 5 1nm为参比波长;芬布芬以 2 83nm为测定波长,340nm为参比波长,在上述波长下,分别测定吸收度值。结果 甲硝唑在 4 1～9 6 μg·ml-1,芬布芬在 3 1～ 7 2 μg·ml-1范围内,浓度与吸收度差值呈良好线性关系,甲硝唑平均回收率为 99 9%(RSD =0 33% ),芬布芬平均回收率为 10 0 0 %( RSD =0 2 7% )。结论 该法简便、快速、准确。
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| 关 键 词： | 牙周康 甲硝唑 芬布芬 双波长分光光度法 含量测定 |
| 文章编号： | 1672-7738(2005)01-0026-02 |
Determination of Yazhoukang by dual wavelength spectrophotometry |
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| Yang Yong-tie,Liu Ying-chun,Wang Hong-gang,Wang Guo-qing,Fei Yi-min.Determination of Yazhoukang by dual wavelength spectrophotometry[J].qilu pharmaceutical affairs,2005,24(1):26-27. |
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| Authors: | Yang Yong-tie Liu Ying-chun Wang Hong-gang Wang Guo-qing Fei Yi-min |
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| Institution: | Yang Yong-tie,Liu Ying-chun1,Wang Hong-gang1,Wang Guo-qing1,Fei Yi-min1 |
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| Abstract: | Objective To determine Metronidazole and Fenbufen contents in Yazhoukang.Methods The contents in Yazhoukang were obtained by dual wavelength spectrophotometry.The absorb values were determined at 314nm and 251nm to Metronidazole,while at 283nm and 340nm to Fenbufen.Results The ranges of linear correlation of Metronidazole and Fenbufen are 4.1～9.6μg·ml -1 and 3.1～7.2μg·ml -1 respectively.The average recoveries of Metronidazole and Fenbufen are 99.9%(RSD=0.33%)and 100.0% (RSD=0.27%) respectively.Conlusion The method is simple,rapid and accurate. |
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| Keywords: | Yazhoukang Metronidazole Fenbufen dual wavelength spectrophotometry content determination |
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