同时性结直肠癌肝转移临床病理因素分析

目的探讨结直肠癌发生肝转移与其临床病理因素的关系.方法分析比较有肝转移117例与Dukes C或D期无肝转移50例结直肠癌病人的临床特点、血清CEA水平、转移淋巴结、以及原发灶的病理类型和静脉侵犯.结果以肝转移灶为首诊原因的有21例,伴肝转移结直肠癌患者远距离淋巴结转移及镜下静脉侵犯发生率升高,与对照组比较差异显著(P＜0.05).结论要重视结直肠癌肝转移的早期诊断,远距离淋巴结转移或镜下静脉侵袭均预示大肠癌发生肝转移的危险性的增加.

Analysis of simultaneous colorectal cancer with hepatic metastasis and its clinic pathologic factors

Objective To investigate the relationship between colorectal cancer with hepatic metastasis and its clinic pathologic factors.Methods The clinical characters,lymph node of metastasis,serum level of CEA,venous invasion and pathologic types of primary lesion were studied in 117 cases with hepatic metastasis and 50 cases of Duckes' C or D stage without hepatic metastasis,respectively.Results Twenty one cases were rapidly deagnosed mainly because of distress suffering from hepatic metastasis, Both venous invasion and distant lymph node of metastasis were significantly more severe ( P <0.05)in the cases of colorectal cancer with hepatic metastasis than those of the control ( P <0.05).Conclusion The early diagnosis of liver metastases from colorectal cancer,distant metastatic lymph nodes or venous invasion under light microscopy is important that may indicate more risk of liver metastasis from colorectal cancer.