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血清降钙素水平在慢性泌尿系统感染定位诊断中的价值
引用本文:邵珊,黄晓光,彭翠英. 血清降钙素水平在慢性泌尿系统感染定位诊断中的价值[J]. 临床医药实践, 2008, 17(1): 20-22
作者姓名:邵珊  黄晓光  彭翠英
作者单位:1. 山西医科大学第二医院,山西,太原,030001
2. 交城县人民医院,山西,交城,030500
摘    要:目的:探讨降钙素原(PCT)对慢性上、下尿路感染的诊断价值。方法:回顾性分析临床确诊慢性肾盂肾炎(CPN)及慢性膀胱炎(CC)的患者血清PCT、全血白细胞(WBC)的变化,判断PCT与泌尿系感染之间的定位关系。PCT的测定采用金标(LUM Itest)法。结果:慢性肾盂肾炎患者组PCT值明显高于下尿路感染组,当血清PCT≥0.5μg/L时,预测肾脏受累的灵敏性和特异性分别为86%和91%,并且随着感染的加重而增加,随着治疗的好转而减少。结论:血清PCT水平的检测对鉴别慢性上、下尿路感染有一定的参考意义。

关 键 词:降钙素原  泌尿道感染  慢性肾盂肾炎  慢性膀胱炎
文章编号:1671-8631(2008)01-0020-03
修稿时间:2007-12-03

The diagnostic value of serum procalcitonin levels in patients with chronic urinary tract infection
SHAO Shan,HUANG Xiao-guang,PEN Cui-ying. The diagnostic value of serum procalcitonin levels in patients with chronic urinary tract infection[J]. Proceeding of Clinical Medicine, 2008, 17(1): 20-22
Authors:SHAO Shan  HUANG Xiao-guang  PEN Cui-ying
Abstract:Objective:To investigate the diagnostic value of procalcitonin(PCT)in the differentianon between chronic pyelonephritis(CPN)and lower urinary tract infection(UTI).Methods:To analyze retrospective the changes of serum PCT in chronic pyelonephritis and chronic cystitis that was clinical definited.Serum PCT was measured by LUMI test metric assay.Results:The plasma levels of PCT in chronic pyelonephritis patients were remarkably higher than those in chronic cystitis.Moreover,the plasma levels of PCT were also correlated with the degree of severity of renal damage.The sensitivity and specificity were 86%and 91%while the cut-off value was chosen as ≥0.5ng/mL.Conclusion:PCT values could be used to differentiate CPN from CC(P<0.01).
Keywords:procalcitonin  urinary tract infections  chronic pyelonephritis  chronic cystitis
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