| 乳腺癌中Ki67、Her-2和nm23的表达及其临床意义 |
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| 引用本文： | 赵鹰,胡长军,王鹏,马斌林,刘虎. 乳腺癌中Ki67、Her-2和nm23的表达及其临床意义[J]. 中国现代药物应用, 2010, 4(18): 18-19 |
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| 作者姓名： | 赵鹰 胡长军 王鹏 马斌林 刘虎 |
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| 作者单位： | 1. 新疆伊犁州友谊医院普外二科,835000
2. 新疆医科大学附属肿瘤医院 |
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| 摘 要： | 目的研究Ki67、Her-2和nm23蛋白在乳腺癌组织中的表达,探讨其临床意义。方法应用免疫组化方法检测104例乳腺癌组织中Ki67、Her-2和nm23蛋白的表达水平。结果 Ki67、Her-2和nm23蛋白表达与乳腺癌淋巴结转移均密切相关。结论联合检测Ki67、Her-2和nm23蛋白表达是衡量乳腺癌预后的重要指标。
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| 关 键 词： | 乳腺癌 Ki67 Her-2 nm23基因蛋白 免疫组织化学 |
Expressions and the clinical significances of Ki67,Her-2 and nm23 in breast cancer |
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| Affiliation: | ZHAO Ying,WANG Peng,MA Bin-lin,et al. |
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| Abstract: | Objective To study the expression of Ki67,Her-2 and nm23 protein in breast cancer,and the relation to biological behavior and prognosis.Methods The expression of Ki67,Her-2 and nm23 protein were determined by immunohistochemistry technique in 104 patients with gastric carcinoma.Results The expression levels of Ki67,HER-2 and nm23 protein were closely correlated with regional lymph node metastasis.Conclusion Combined analysis of Ki67,HER-2 and nm23 protein expression showed that were important indicator for judging the prognosis of breast cancer. |
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| Keywords: | Ki67 Her-2 |
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