| 肺炎支原体或衣原体感染与系统性红斑狼疮关系的研究 |
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| 引用本文： | 王玉宝,魏殿军,何屏,宋诗铎.肺炎支原体或衣原体感染与系统性红斑狼疮关系的研究[J].天津医科大学学报,2006,12(2):187-189. |
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| 作者姓名： | 王玉宝 魏殿军 何屏 宋诗铎 |
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| 作者单位： | 1. 天津医科大学第二医院感染性疾病研究所,天津,300211
2. 天津医科大学第二医院检验科 |
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| 基金项目： | 天津医科大学科研基金资助项目(2000KY10) |
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| 摘 要： | 目的:探讨肺炎支原体或衣原体感染与系统性红斑狼疮(SLE)的关系。方法:运用ELISA法定量检测40例SLE患者和40例年龄、性别相对应的健康人群血清中肺炎支原体IgG抗体和衣原体IgG抗体。结果:病例组肺炎支原体IgG阳性率47.5%,较对照组(25.0%)明显增高,抗体阳性者的抗体活度无统计学差异。病例组衣原体IgG阳性率42.5%,与对照组(50.0%)无统计学差异,抗体阳性者的抗体活度也无统计学差异。结论:SLE和肺炎支原体感染有关,肺炎支原体感染可能对SLE发病起促进作用。未发现SLE和衣原体感染有关。
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| 关 键 词： | 系统性红斑狼疮 肺炎支原体 衣原体 |
| 文章编号： | 1006-8147（2006）02-0187-03 |
| 收稿时间： | 2006-01-04 |
| 修稿时间： | 2006年1月4日 |
Relationship between mycoplasma pneumoniae or chlamydia infection and systemic lupus erythematosus |
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| WANG Yu-bao,WEI Dian-jun,HE Ping,SONG Shi-duo.Relationship between mycoplasma pneumoniae or chlamydia infection and systemic lupus erythematosus[J].Journal of Tianjin Medical University,2006,12(2):187-189. |
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| Authors: | WANG Yu-bao WEI Dian-jun HE Ping SONG Shi-duo |
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| Institution: | 1.Institute of Infectious Diseases,The Second Hospital, Tianjin Medical University, Tianjin 300211, China 2.Department of Laboratory Diagnostic,The Second Hospital, Tianjin Medical University |
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| Abstract: | Objective: To investigate the correlation between mycoplasma pneumoniae or chlamydia infection and systemic lupus erythematosus.Methods: The serum IgG antibodies of mycoplasma pneumoniae or chlamydia from 40 SLE patients and 40 age-sex-matched healthy subjects were tested by quantitative ELISA.Results: The positive rate of IgG antibodies of mycoplasma pneumoniae was 47.5% in SLE patients.It is significantly higher than that in control(25.0%)(P<0.05).There was no obvious difference in the positive ratio of IgG antibodies of chlamydia between two groups.Antibody activities of mycoplasma pneumoniae or chlamydia in positive were not significantly different between two groups.Conclusion: SLE is correlated to mycoplasma pneumoniae infection,which may potentiate an attack of SLE.Correlation between SLE and IgG antibodies to Chlamydia is not found. |
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| Keywords: | Systemic lupus erythematosus Mycoplasma pneumoniae Chlamydia |
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