A new Erythrina alkaloid from Erythrina herbacea |
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Authors: | Hitoshi Tanaka Hisanori Hattori Toshihiro Tanaka Eiji Sakai Nobuyuki Tanaka Aditya Kulkarni Hideo Etoh |
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Affiliation: | (1) Faculty of Pharmacy, Meijo University, Yagoto, Tempaku-ku, Nagoya 468-8503, Japan;(2) Gifu Pharmaceutical University, Mitahora-higashi, Gifu 502-8585, Japan;(3) The Kochi Prefectural Makino Botanical Garden, Godaisan, Kochi 781-8125, Japan;(4) Faculty of Agriculture, Shizuoka University, Shizuoka 422-8529, Japan |
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Abstract: | A new Erythrina alkaloid, 10-hydroxy-11-oxoerysotrine (1), has been isolated from the flowers of Erythrina herbacea together with five known compounds: erytharbine (2), 10,11-dioxoerysotrine (3), erythrartine (4), erysotramidine (5) and erysotrine-N-oxide (6). The structure of the new compound was elucidated on the basis of its spectral data, including 2-D NMR and mass (MS) spectra. The new compound is a rare C-10 oxygenated Erythrina alkaloid. The antioxidant activities of the isolated compounds 1–6 were evaluated by scavenging with peroxynitrite. |
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Keywords: | Erythrina herbacea L. Leguminosae Erythrina alkaloids 10-hydroxy-11-oxoerysotrine Antioxidant activity Peroxynitrite |
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