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A new Erythrina alkaloid from Erythrina herbacea
Authors:Hitoshi Tanaka  Hisanori Hattori  Toshihiro Tanaka  Eiji Sakai  Nobuyuki Tanaka  Aditya Kulkarni  Hideo Etoh
Affiliation:(1) Faculty of Pharmacy, Meijo University, Yagoto, Tempaku-ku, Nagoya 468-8503, Japan;(2) Gifu Pharmaceutical University, Mitahora-higashi, Gifu 502-8585, Japan;(3) The Kochi Prefectural Makino Botanical Garden, Godaisan, Kochi 781-8125, Japan;(4) Faculty of Agriculture, Shizuoka University, Shizuoka 422-8529, Japan
Abstract:
A new Erythrina alkaloid, 10-hydroxy-11-oxoerysotrine (1), has been isolated from the flowers of Erythrina herbacea together with five known compounds: erytharbine (2), 10,11-dioxoerysotrine (3), erythrartine (4), erysotramidine (5) and erysotrine-N-oxide (6). The structure of the new compound was elucidated on the basis of its spectral data, including 2-D NMR and mass (MS) spectra. The new compound is a rare C-10 oxygenated Erythrina alkaloid. The antioxidant activities of the isolated compounds 16 were evaluated by scavenging with peroxynitrite.
Keywords:Erythrina herbacea L.  Leguminosae   Erythrina alkaloids  10-hydroxy-11-oxoerysotrine  Antioxidant activity  Peroxynitrite
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