早期肠内营养在重症急性胰腺炎治疗中的应用价值

目的探讨早期肠内营养在重症急性胰腺炎（SAP）治疗中的应用价值。方法将62例SAP患者按入院先后顺序,随机分为肠内营养（EN）组31例和常规治疗组（常规组）31例。观察两组治疗结果及临床指标的变化。结果 2周后,两组患者的APACHEⅡ评分、CTSI较前显著降低,且EN组的各项评分均显著低于常规治疗组,差异均有统计学意义（均P〈0.01）。营养支持后两周EN组的血糖、血清白蛋白、血钙和血肌苷均较治疗前有显著改善,差异有统计学意义（P〈0.05）,同时,EN组平均住院天数明显缩短,中转手术率、感染率、病死率方面也明显低于常规治疗组,差异均有统计学意义（均P〈0.05）。结论 EN治疗SAP疗效优于常规治疗,且安全、可行,应在临床推广应用。

Application evaluation of early enteral nutrition on treatment of severe acute pancreatitis

Objective To investigate the role of enteral nutrition support in treatment of acute severe pancreatitis.Methods The data of 62 patients with SAP were retrospectively analyzed.They were randomly assigned to receive either enteral nutrition（EN group,n=31）or given conventional therapy（n=31）.The clinical indicators were recorded.Results Two weeks after nutritional support,the APACHE Ⅱ score and CTSI score were significantly lower in the EN group than given conventional therapy group（P〈0.01）.The blood glucose,serum albumin,the blood calcium and serum creatinine in both groups were notably improved（P〈0.05）.The average hospital stay was also notably shortened in the EN group.The incidence of shift to operation,complications and mortality were significantly lower in the EN group than that in the given conventional therapy group（P〈0.05）.Conclusion Enteral nutrition is safe and effective in treatment of SAP.