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糖尿病患者血清sIL-2R测定及临床意义
引用本文:郭军,高立民,马宏岩,王建军. 糖尿病患者血清sIL-2R测定及临床意义[J]. 黑龙江医药科学, 1997, 0(4)
作者姓名:郭军  高立民  马宏岩  王建军
作者单位:泰安市中心医院内分泌科,泰安市中心医院内分泌科,泰安市中心医院内分泌科,山东农大校医院
摘    要:
采用酶联免疫吸附法(ELISA)技术,对25例IDDM患者治疗前后及40例NIDDM患者血清可溶性sIL-2R水平进行测定。结果发现:IDDM患者血清sIL-2R明显高于正常对照组,经治疗后血清sIL-2R水平下降;而NIDDM患者血清sIL-2R无明显变化。因此血清sIL-2R水平变化及动态观察可作为机体免疫系统激活状态的指标之一,及IDDM患者诊断,治疗和预后的监测指标。

关 键 词:糖尿病  sIL-2R

Clinical significance in determination of serum slL-2R levels in patients with DM
Guo Jun. Clinical significance in determination of serum slL-2R levels in patients with DM[J]. Heilongjiang Medicine and Pharmacy, 1997, 0(4)
Authors:Guo Jun
Abstract:
The Serum Levels of Soluable interleukin-2 receptor(sIL-2R)in 25 patients with IDDM and in 40 patients with NIDDM were measured using a sand with enzyme-Linded immunosorbent assay(ELISA).The results showed that serum sIL-2R levels in patients with IDDM were significantly bighter than those of the controlsgroup. After treament sIk-2R levels were declined greatly compared with the pretreatment ones and sIL-2R levels in patients with NIDDM were not changed grealy.Therefore,the change and eonsecutive observation of serum sIL-2R levels is helpful to the activated state of immunitiy, diagnosis,treatment and prognosis.
Keywords:DM  slL-2R
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