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视杆细胞视觉传导的慢快通道及临床应用研究进展
引用本文:冯超,杨安怀,陈长征. 视杆细胞视觉传导的慢快通道及临床应用研究进展[J]. 眼科研究, 2009, 27(6): 540-543
作者姓名:冯超  杨安怀  陈长征
作者单位:武汉大学人民医院眼科,430060
摘    要:视杆细胞对视觉,特别是暗视觉的形成具有重要的作用。视杆细胞与神经节细胞之间视觉传导的具体通道和过程目前尚不清楚。20年前,国外学者认识到在视网膜视杆细胞与神经节细胞之间的视觉传导可能并非只存在一条通道。在15Hz频率下,利用暗适应闪烁光视网膜电图(ERG)可将视杆细胞慢快通道的各自反应分离出来。某些疾病,如视网膜色素变性(RP)、Stargardt黄斑营养不良、完全性静止性夜盲的暗适应15Hz闪烁光ERG反应则表现出某些特性。就视杆细胞多条视觉传导通道的发现、传导途径及临床应用进行综述。

关 键 词:视杆细胞  慢通道  快通道  视网膜神经节细胞

Clinical application of rod slow and fast pathway
Feng Chao,Yang Anhuai,Chen Changzheng. Clinical application of rod slow and fast pathway[J]. Chinese Ophthalmic Research, 2009, 27(6): 540-543
Authors:Feng Chao  Yang Anhuai  Chen Changzheng
Affiliation:Feng Chao , Yang Anhuai, Chen Changzheng( Renmin Hospital of Wuhan University, Wuhan 430060, China)
Abstract:Retinal rod cells play an important role in human vision function,especially dark vision. The substantial pathway and process of visual transmission between retinal rod cells and retinal ganglion cells is still uncertain. Some researchers had found that not only one pathway exist between retinal rod cells and retinal ganglion cells during the visual transmission since 20 years ago. Recently, the study progress in retinal rod muhipathway during the visual transmission is concerned by more and more researchers. The separately responses of the rod slow and fast pathway can be seen with 15 Hz flash ERG after dark adaptation. There are some characteristics in 15 Hz flash ERG responses of patients with retinitis pigmentosa, stargardt' s macular dystrophy, complete stationary night blindness. The studing process, visual transmission and clinical application of rod multipathway were introduced in this paper.
Keywords:retinal rod cell  slow pathway  fast pathway  retinal ganglion cells
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