连续气流通气对犬血流动力学的影响

目的：观察连续气流通气期间气道压力及流量对犬血流动力学的影响。方法：选用健康犬９只，在全麻肌松下，分别采用两种气道压（０ｃｍＨ２Ｏ，３ｃｍＨ２Ｏ），３种不同气体流量（０６，０８，１０Ｌ·ｋｇ－１／ｍｉｎ）进行ＣＦＶ，每种通气方式维持３０ｍｉｎ后抽取股动脉血作血气分析，同时，测定各种通气组合时的血流动力学参数，并与间歇正压通气（ＩＰＰＶ）比较。结果：ＣＦＶ时，各组中心静脉压显著低于ＩＰＰＶ时值（Ｐ＜００５），其余指标无显著差异。各组ＰａＣＯ２在正常范围。结论：ＣＦＶ时，对循环功能无不良影响，由于气道内压低，故中心静脉压明显降低。

Effects of Airway Pressure and Flow Rate on Hemodynamics during Constant Flow Ventilation in Dogs

Objective:To evaluate the effects of different airway pressures and flow rates on hemodynamics during constant flow ventilation in dogs.Methods:Two lower airway pressures and three gas flow rates (0.6 L·kg -1 /min,0.8 L·kg -1 /min,1.0 L·kg -1 /min) were used during CFV in nine anesthetized and paralyzed dogs.After 30 min of each CFV mode arterial blood gases and hemodynamic values were measured and compared with those of IPPV.Result:Normal PaCO 2 can be maintained during CFV and the central venous pressure of each CFV mode has significantly decreased compared with that of IPPV ( P <0.05).Conclusion:A lower positive airway pressure and a lower flow rate contribute to maintaining adequate lung gas exchange and the central venous pressure is low because of lower mean airway pressure during CFV.