芪参益气滴丸对冠心病PCI术后气虚血瘀证患者中医症状积分及西雅图心绞痛量表影响的临床观察

[目的]观察芪参益气滴丸对冠心病经皮冠状动脉介入治疗(PCI)术后气虚血瘀证患者中医症状积分、西雅图心绞痛量表的变化.[方法]纳入2019年3月—2019年10月在天津市胸科医院心内科确诊为冠心病PCI术后气虚血瘀证的患者164例,分为对照组、试验组,每组各82例.对照组给予标准的冠心病二级预防方案进行治疗,试验组在对...

Clinical observation of the effect of Qishen Yiqi Dripping Pill on traditional Chinese medicine syndromes scores and Seattle angina pectoris scale of patients with qi deficiency and blood stasis syndrome after PCI operation of coronary heart disease

[Objective] To observe the changes of Qishen Yiqi Dripping Pill on traditional Chinese medicine (TCM) syndrome scores and Seattle Angina Pectoris Scale in patients with qi deficiency and blood stasis syndrome after percutaneous coronary intervention(PCI) operation of coronary heart disease.[Methods] A total of 164 patients who were diagnosed with qi deficiency and blood stasis syndrome after PCI in the department of cardiology of Tianjin Chest Hospital from March 2019 to October 2019 were included. They were divided into two groups including control group and test group, each group had 82 cases. The control group was treated with a standard secondary prevention plan for coronary heart disease, and the test group was treated with Qishen Yiqi Dripping Pill on the basis of the treatment plan of the control group. The observation course of treatment was 1 month. Observation indicators included the patients'' baseline data, TCM syndrome scores, and Seattle angina pectoris scale.[Results] In terms of TCM syndrome scores, after treatment, the scores of chest pain, chest tightness, palpitations, shortness of breath, and dark purple lips and the total scores of patients in test group were significantly lower than those of control group (P<0.05 or P<0.01). In terms of the amount of Seattle angina pectoris scale, after treatment, the patients in test group were significantly lower than those in control group in terms of physical limitation, stable angina pectoris, angina attacks, and satisfaction with treatment (P<0.01). Cluster analysis and Pearson correlation analysis showed that the degree of physical limitation was positively correlated with the primary syndrome such as shortness of breath and fatigue, and the degree of treatment satisfaction and disease awareness were positively correlated with the secondary syndrome such as dark purple lips (P<0.05 or P<0.01).[Conclusion] Qishen Yiqi Dripping Pill can significantly improve the clinical efficacy of patients after PCI, and significantly improve the TCM syndromes and quality of life of patients with qi deficiency and blood stasis syndrome. Through the combination of TCM syndrome scores and Seattle angina pectoris scale analysis, it could provide reference for clinical differentiation and the use of Qishen Yiqi Dripping Pill to treat coronary heart disease with qi deficiency and blood stasis syndrome.