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The redox tolerance test as a measure of hepatic function in patients with obstructive jaundice
Affiliation:1. Department of Chemistry, Faculty of Science and Letters, Marmara University, 34722 Göztepe, Istanbul, Turkey;2. Department of Chemistry, Faculty of Arts&Science, Yildiz Technical University, TR34210 Istanbul, Turkey;3. Department of Metallurgical and Materials Engineering, Faculty of Chemistry-Metallurgical, Yildiz Technical University, TR34210 Istanbul, Turkey;4. Department of Chemical Engineering, Engineering Faculty, Marmara University, 34722 Göztepe, Istanbul, Turkey;1. Surface Coating and Corrosion Department, Institute for Color Science and Technology, Tehran, Iran;2. Polymer Engineering Department, Amirkabir University of Technology, Tehran, Iran;1. School of Materials Sciences, Indian Association for the Cultivation of Science, 2A & 2B Raja S. C. Mallick Road, Jadavpur, Kolkata 700032, India;2. Institute of Nano Science and Technology, Sector-81, Mohali 140306, Punjab, India;3. School of Physical Sciences, Indian Association for the Cultivation of Science, 2A & 2B Raja S. C. Mallick Road, Jadavpur, Kolkata 700032, India;4. Department of Chemistry, University of Kalyani, Kalyani 741235, India;5. UGC-DAE Consortium for Scientific Research, University Campus, Khandwa Road, Indore 452001, India
Abstract:
The redox tolerance test was performed before percutaneous transhepatic biliary drainage, in 15 patients with obstructive jaundice, and repeated 2 weeks after. Four patients without jaundice were evaluated as a control group. No difference was found in the redox tolerance index between the controls and the group with good bilirubin clearance. On the contrary, the redox tolerance index was significantly lower in the group with poor bilirubin clearance. No significant change in the redox tolerance index was revealed after percutaneous drainage. However, of four patients whose indices were smaller than 0.5 before biliary drainage, three died after developing cholangitis. The redox tolerance test is useful for evaluating hepatic function and predicting outcome in patients with obstructive jaundice.
Keywords:
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