Selective enrichment of hematopoietic progenitor cells from peripheral blood期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Selective enrichment of hematopoietic progenitor cells from peripheral blood

Affiliation:	1. Department of Biology, University of York, York, England, UK;2. Department of Genetics, Stanford University School of Medicine, Stanford, California;3. Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH), Heidelberg, Germany;4. Division of Inflammatory Stress in Stem Cells, German Cancer Research Center (DKFZ), Heidelberg, Germany;5. International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Japan;6. European Molecular Biology Laboratory (EMBL), Heidelberg, Germany;7. Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan;8. Division of Stem Cells and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany

Abstract:	We tried to improve progenitor cell yields by different modifications on conventional leukocyte separation protocols to obtain a more selective stem cell enrichment from peripheral blood. Our data suggest that especially higher process volumes allow selective increases of progenitor cell recoveries. Differences in stem cell yields according to different malignancies are discussed.

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