Clinical significance of obstructive sleep apnea in middle aged and elderly |
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| Authors: | S Ayik G Akhan |
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| Institution: | 1. Department of Chest Diseases, Izmir Ataturk Research and Training Hospital, Izmir, Turkey;2. Department of Neurology, Izmir Ataturk Research and Training Hospital, Izmir, Turkey;1. Senior maxillofacial prosthetist, Maxillofacial Department, King’s College Hospital, London, UK;2. Consultant maxillofacial prosthetist, Maxillofacial Department, Queens Medical Centre, Nottingham University Hospital Trust, Nottingham, UK;3. Consultant maxillofacial surgeon, Maxillofacial Department, Queens Medical Centre, Nottingham University Hospital Trust, Nottingham, UK;1. Lecturer, Department of Biomedical Engineering, Yonsei University College of Medicine, Seoul, Republic of Korea;2. Clinical Instructor, Department of Ophthalmology, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Republic of Korea;3. Technician, Department of Ophthalmology, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Republic of Korea;4. Professor, Department of Ophthalmology, Severance Hospital, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Republic of Korea;1. Department of Psychiatry, University of Oxford, Oxford, UK;2. Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil;3. MRC/Wits Rural Public Health and Health Transitions, Research Unit (Agincourt), School of Public Health, University of the Witwatersrand, Johannesburg, South Africa;4. Post-Graduate Program in Health and Behavior, Catholic University of Pelotas, Pelotas, RS, Brazil;5. Department of Preventive Medicine, School of Medicine, University of Sao Paulo, São Paulo, Brazil;1. Pôle anesthésie, réanimations chirurgicales, Samu, Hôpitaux universitaires de Strasbourg, Nouvel Hôpital civil, 1, place de l’Hôpital, BP 426, 67091 Strasbourg cedex, France;2. Service de chirurgie cardiaque, Hôpitaux universitaires de Strasbourg, Nouvel Hôpital civil, 1, place de l’Hôpital, BP 426, 67091 Strasbourg cedex, France;3. Service de chirurgie vasculaire et transplantation rénale, Hôpitaux universitaires de Strasbourg, Nouvel Hôpital civil, 1, place de l’Hôpital, BP 426, 67091 Strasbourg cedex, France;4. Service de radiologie, Hôpitaux universitaires de Strasbourg, Nouvel Hôpital civil, 1, place de l’Hôpital, BP 426, 67091 Strasbourg cedex, France;1. Associate Professor, Department of Conservative Dentistry, School of Dental Medicine, University Hospital Heidelberg, Heidelberg, Germany;2. Dentist, Department of Conservative Dentistry, School of Dental Medicine, University Hospital Heidelberg, Heidelberg, Germany;3. Statistician, Institute of Medical Biometry and Informatics, Ruprecht Karls University Heidelberg, Heidelberg, Germany;4. Statistician, Institute of Medical Biometry and Informatics, Ruprecht Karls University Heidelberg, Heidelberg, Germany;5. Associate Professor, Department of Conservative Dentistry, School of Dental Medicine, University Hospital Heidelberg, Heidelberg, Germany;1. Chest Department, Faculty of Medicine, Menoufia University, Egypt;2. Gynecological & Obstetrics Department, Faculty of Medicine, Menoufia University, Egypt;3. Public Health & Community Medicine Department, Faculty of Medicine, Menoufia University, Egypt |
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| Abstract: | ObjectivesThe aim of the present study is to compare the clinical characteristics of obstructive sleep apnea between elderly (age ≥ 65 years) and middle aged (age ≥ 25 and < 65 years) patients.Patients and methodsA retrospective study was performed in patients referred for daytime sleepiness, habitual nocturnal snoring and witnessed apnea spells, from 2008 to 2011. Patients with obstructive sleep apnea were classified into two groups according to age at first identification of respiratory pauses during sleep: an elderly onset group (n = 116) and, randomly selected middle aged control group (n = 116). The demographic characteristics, clinical presentations, Epworth sleepiness scale (ESS) and polysomnographic variables were compared between groups.ResultsSleep efficacy was significantly lower in the elderly group. No significant differences in body mass index (BMI), neck circumference, ESS, apnea hypopnea index (AHI) or O2 saturation indexes were seen between elderly and middle aged groups. As for variables by gender in the elderly group, no significant differences in BMI, neck circumference, ESS, sleep efficacy or AHI were seen between female and male patients in the elderly group. Mean O2 saturation and lowest O2 saturation indexes were significantly lower in female patients.ConclusionsOur data suggest that the clinical characteristics of obstructive sleep apnea in the elderly onset group seemed to remain milder when compared with the middle aged patients. This finding may be due to the smaller physiologic response to respiratory events. Also, the clinical presentations between female and male patients in the elderly group were found almost similar in the study group. |
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