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地塞米松对小鼠前胃鳞状上皮增生癌变作用的实验研究
引用本文:杜华贞,付怀平,千高峰,和瑞芝,常东明.地塞米松对小鼠前胃鳞状上皮增生癌变作用的实验研究[J].新乡医学院学报,1989(1).
作者姓名:杜华贞  付怀平  千高峰  和瑞芝  常东明
作者单位:新乡医学院病理学教研室,新乡医学院病理学教研室,新乡医学院病理学教研室,新乡医学院病理学教研室,新乡医学院药理学教研室
摘    要:本文就地塞米松对小鼠前胃上皮增生、癌变作了实验研究。结果表明,地塞米松对小鼠前胃上皮有促癌作用。癌变率:实验70天为32.62%,120天为42.47%。讨论了地塞米松促进小鼠前胃上皮增生、癌变与免疫功能低下及细胞代谢受抑制有关。

关 键 词:地塞米松  前胃  增生  癌变

EFFCT OF DXM ON CANCERATION AND HYPERPLASIA OF THE FORESTOMACH IN MOUSE
Du Huazheng,et al.EFFCT OF DXM ON CANCERATION AND HYPERPLASIA OF THE FORESTOMACH IN MOUSE[J].Journal of Xinxiang Medical College,1989(1).
Authors:Du Huazheng  
Institution:Department of Pathology
Abstract:A study was made in the mouse's forestomach to test the effects of DXM on the squamous epithelial proliferate and the carcinogenesis. The result shows that DXM can lead to the carcinogenesis in the forestomach epithelial of the mice. After 70 days of test, the carcinogenicity rate is 32.62%, after 120 days, 42.47%. DXM would promote the carcinogenesis and the proliferate in the mouse's forestomach. The low function of the immune is related to the metabolic inhibition cf the cells.
Keywords:DXM  forestomach  hyperplasia  canceration
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