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左旋氨氯地平治疗老年高血压患者的疗效观察
引用本文:王富贵,王慧,李文华,徐通达. 左旋氨氯地平治疗老年高血压患者的疗效观察[J]. 中国实用医药, 2009, 4(22): 21-22
作者姓名:王富贵  王慧  李文华  徐通达
作者单位:1. 222100,徐州医学院附属医院药剂科,221002
2. 徐州市中医院药剂科
3. 徐州医学院附属医院心内科
摘    要:
目的评价左旋氨氯地平治疗老年性高血压的有效性和安全性。方法68例原发性高血压患者服用左旋氨氯地平,疗程6个月。结果68例患者中显效42例(61.7%),有效22例(32.3%),无效4例(6.O%)总有效率97.1%,治疗2周后与治疗前比较,坐位血压明显下降,治疗前为(157±15)/(102±12)mmHg,治疗后为(142±12)/(92±6)mmHg,但心率无明显变化(P〉0.05)。检测24h动态血压,计算降压谷峰比值率〉65%。结论左旋氨氯地平治疗老年性高血压安全有效。

关 键 词:左旋氨氯地平  高血压

The therapeutic effect of in the treatmen t in old patients with essential hypertension using Levamlodipine besylate tablets
Affiliation:WANG Fu-gui, WANG Hui, LI Wen-hua, et al( PHarmap harmaceutial preparation section and cardiology Department of the Affilated Hospital of Xuzhou Medical college, Jiangsu ,221002, China )
Abstract:
Objective To evaluate of the effectiveness and safety of Levamlodipine Besylate tablets in the treatment in old patients with essential hypertension. Methods 68 cases of essential hypertension taking Le- vamlodipine Besylate Tablets, course of 6 months. Results Markedly effective in 42 cases(61.7% ) , effctive in 22 cases(32. 3% ,invalid in 4 cases(6. 0% ) ,and the total effective power was 97.1%. Sitting blood pressure decreased significantly two weeks after treatment compared with before treatment, before treatment: ( 157 ± 15 )/ ( 102 ± 12) mm Hg; after treatment: ( 142 ±12/92 ± 6) mm Hg. No significant change on heart rate ( P 〉 0. 05 ). Detection of 24-hour ambulatory blood pressure and alculate the ratio of buck-peak rate 〉 65%. Conclusions In the treatment of essential hypertension in old patients, Levamlodipine besylate tablets is safe and effective.
Keywords:Levamlodipine besylate tablets  Hypertension
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