| 乙型和丙型肝炎病毒感染与慢性肝病 |
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| 引用本文： | 贾彦征,李冬田,任中原,李灼亮,余宙耀. 乙型和丙型肝炎病毒感染与慢性肝病[J]. 临床肝胆病杂志, 1999, 15(1): 34-36 |
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| 作者姓名： | 贾彦征 李冬田 任中原 李灼亮 余宙耀 |
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| 作者单位： | 1. 510602,空军广州医院中国人民解放军传染病中心
2. 天津医科大学 |
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| 摘 要： | 检测天津地区１１９例慢性肝病毒者ＨＢＶ、ＨＣＶ标志,并对其中２８例ＨＣＶＲＮＡ阳性血清进行基因分型。结果,ＨＢＶ感染率明显高于ＨＣＶ感染率（Ｐ〈０．０５）,肝癌患者中ＨＢＶ、ＨＣＶ重叠感染率明显高于慢性肝炎（Ｐ〈０．０５）;各组均以ＨＣＶⅡ型为主。提示天津地区慢性肝病上前仍以ＨＢＶ感染为主;ＨＢＶ、ＨＣＶ重叠感染对肝癌的发生似有相加作用;ＨＣＶⅡ型感染在天津地区ＨＣＶ相关性曙性肝病中可以起主要作用
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| 关 键 词： | 乙型肝炎病毒 丙型肝炎病毒 重叠感染 基因分型 |
| 修稿时间： | 1997-12-21 |
Hepatitis B and Hepatitis C Virus infection and chronic liver disease |
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| JiaYanzheng,LiDongtain,RenZhongyuan,etalResearchCentreforInfectiousDiseaseofPLAGuangzhou. Hepatitis B and Hepatitis C Virus infection and chronic liver disease[J]. Chinese Journal of Clinical Hepatology, 1999, 15(1): 34-36 |
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| Authors: | JiaYanzheng LiDongtain RenZhongyuan etalResearchCentreforInfectiousDiseaseofPLAGuangzhou |
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| Affiliation: | JiaYanzheng,LiDongtain,RenZhongyuan,etalResearchCentreforInfectiousDiseaseofPLAGuangzhou510602 |
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| Abstract: | WedetectedmarkersofHBVandHCVof119patientswithchronicliverdisease28HCVRNApositiveserawereanalyzedbyRFLPThedateshowedtheinfectionrateofHBVwassignificantlyhigherthanthatofHCV,( PWTBZ<005);superinfectionrateofHBVandHCVofHepatocellularCarcinomawassignificantlyhigherthanthatofchronichepatitis,( P <005);superinfectionrateofHBVandHCVofHepatocellularCarcinomawassignificantlyhigherthanthatofchronichepatitis,( P <005);HCVgenotypesofallgroupsweremainlyoftypeTheseresultsindicatedHBVwasstillthemainpathogenicfactorofchronicliverdiseaseinTianjinarea,superinfectionmayacceleratetheprogressoflivercancer;HCVtypeappearedtoplayamainroleinthedevelopmentofHCVassociatedchronicliverdisease |
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| Keywords: | HBVHCVsuperinfectionRELP |
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