|
|||||
|
|
| Non-alcoholic fatty liver disease and the metabolic syndrome： An update | |
| 引用本文： | Rector RS,Thyfault JP,Wei Y,Ibdah JA. Non-alcoholic fatty liver disease and the metabolic syndrome： An update[J]. World journal of gastroenterology : WJG, 2008, 14(2): 185-192. DOI: 10.3748/wjg.14.185 |
| 作者姓名： | Rector RS Thyfault JP Wei Y Ibdah JA |
| 作者单位： | Division of Gastroenterology and Hepatology University of Missouri Columbia MO 65212 United States,Division of Gastroenterology and Hepatology Harry S. Truman Memorial Veterans Medical Center and Departments of Nutritional Sciences University of Missouri Columbia MO 65212 United States,Division of Gastroenterology and Hepatology Harry S. Truman Memorial Veterans Medical Center and Departments of Medical Pharmacology and Physiology University of Missouri Columbia MO 65212 United States |
| 摘 要： | Sedentary lifestyle and poor dietary choices are leading to a weight gain epidemic in westernized countries, subsequently increasing the risk for developing the metabolic syndrome and nonalcoholic fatty liver disease （NAFLD）. NAFLD is estimated to affect approximate 30% of the general US population and is considered the hepatic manifestation of the metabolic syndrome. Recent findings linking the components of the metabolic syndrome with NAFLD and the progression to nonalcoholic steatohepatitis （NASH） will be reviewed; in particular, the role of visceral adipose tissue, insulin resistance, and adipocytokines in the exacerbation of these conditions. While no therapy has been proven effective for treating NAFLD/NASH, common recommendations will be discussed. |
| 关 键 词： | 非酒精性脂肪肝 代谢综合症 胰岛素抵抗 饮食习惯 |
| 收稿时间： | 2007-07-25 |
Non-alcoholic fatty liver disease and the metabolic syndrome: an update |
|
| Rector R Scott,Thyfault John P,Wei Yongzhong,Ibdah Jamal A. Non-alcoholic fatty liver disease and the metabolic syndrome: an update[J]. World journal of gastroenterology : WJG, 2008, 14(2): 185-192. DOI: 10.3748/wjg.14.185 | |
| Authors: | Rector R Scott Thyfault John P Wei Yongzhong Ibdah Jamal A |
| Affiliation: | 1. Division of Gastroenterology and Hepatology,University of Missouri,Columbia,MO 65212,United States 2. Division of Gastroenterology and Hepatology,Harry S.Truman Memorial Veterans Medical Center,and Departments of Nutritional Sciences,University of Missouri,Columbia,MO 65212,United States 3. Division of Gastroenterology and Hepatology,Harry S.Truman Memorial Veterans Medical Center,Univerity of Missouri,Columbia,MO 65212,United States 4. Division of Gastroenterology and Hepatology,Harry S.Truman Memorial Veterans Medical Center,and Departments of Medical Pharmacology and Physiology,University of Missouri,Columbia,MO 65212,United States |
| Abstract: | Sedentary lifestyle and poor dietary choices are leading to a weight gain epidemic in westernized countries,subsequently increasing the risk for developing the metabolic syndrome and nonalcoholic fatty liver disease (NAFLD). NAFLD is estimated to affect approximate 30% of the general US population and is considered the hepatic manifestation of the metabolic syndrome.Recent findings linking the components of the metabolic syndrome with NAFLD and the progression to nonalcoholic steatohepatitis (NASH) will be reviewed;in particular, the role of visceral adipose tissue, insulin resistance, and adipocytokines in the exacerbation of these conditions. While no therapy has been proven effective for treating NAFLD/NASH, common recommendations will be discussed. |
| Keywords: | Nonalcoholic fatty liver disease Metabolic syndrome Insulin resistance Cytoldnes Inflammation |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |