全杜仲胶囊联合左旋氨氯地平治疗肝肾阴虚型肾性高血压随机平行对照研究

[目的]观察全杜仲胶囊联合左旋氨氯地平治疗肝肾阴虚型肾性高血压疗效。[方法]使用随机平行对照方法,将218例住院患者按随机数字表法随机分为两组,均低盐低脂优质蛋白饮食,适当控制水分摄入,纠正贫血、血液透析等。对照组106例左旋氨氯地平片(吉林省天风制药有限责任公司生产),5mg/次,2次/d。治疗组112例左旋氨氯地平用法同对照组,全杜仲胶囊口服,4～6粒/次,2次/d。观测临床症状、血压、心电图。4周为1疗程,连续治疗1疗程,随访2个月,判定疗效。[结果]症状、血压及心电图两组均有不同改善,治疗组改善均优于对照组(P<0.05);收缩压、舒张压两组均有改善(P<0.05),治疗组改善优于对照组(P<0.01);心电图两组均有改善(P<0.05),治疗组改善优于对照组(P<0.05)。[结论]纯中药制剂全杜仲胶囊,具有纯度高,不需煎煮,服用方便的特点,未发现有副作用,联合左旋氨氯地平治疗肝肾阴虚型肾性高血压效果满意,值得临床推广。

The Randomized Controlled Study of Quanduzhong Capsule Jiont Levamlodipine to Cure Renal Hypertension for Ganshenyinxu

[Objective]To Observed the Efficacy of Quanduzhong Capsule jiont Levamlodipine to cure renal hypertension for ganshenyinxu.[Method] To the Randomized controlled study,By the random number table to Care the 218 cases Hospitalized patients fore Two GroupS,All give Low-salt low-fat high-quality protein diet,Proper control of water intake,Correction of anemia,Hemodialysis Etc.The 106 cases of Control group only use Levamlodipine(production by Tianfeng Pharmaceutical Co.,Ltd.Of Jilin Province),5mg one time,Twice a day;The 112 cases of Treatment group notonly give Levamlodipine the same to Control group,but also jiont Quanduzhong Capsule,4 to 6 tablets of each,Twice a day.Observed Clinical symptoms,Blood pressure,ECG,Four weeks of a course of treatment,Continuous treatment of a course of treatment,Were followed up for 2 months,Determine the efficacy.[Result]The Symptoms、Blood pressure、ECG Were improved fore Two groups,But the treatment group improved more significantly than the control group(P<0.05),Systolic blood pressure,diastolic blood pressure in both groups improved(P<0.05),treatment group is better than control group(P<0.01),ECG in both groups improved(P<0.05),But the treatment group improvement than the control group(P<0.05).[Conclusion]The Pure Chinese medicine of Quanduzhong Capsule,With high purity、Without boiling、Easy to take,Not have side effects,The United levamlodipine satisfied with the effect of amlodipine in the treatment of ganshenyinxuxing-renal hypertension,Worthy of clinical.