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Origin and evolution of operons and metabolic pathways
Authors:Marco Fondi   Giovanni Emiliani  Renato Fani  
Affiliation:aLaboratory of Microbial and Molecular Evolution, Department of Evolutionary Biology, Via Romana 17-19, University of Florence, 50125 Florence, Italy;bDepartment of Environmental and Forestry Sciences, University of Florence, via S. Bonaventura 13, 50145 Florence, Italy
Abstract:The emergence and evolution of metabolic pathways represented a crucial step in molecular and cellular evolution, allowing primitive organisms to become less dependent on exogenous sources of organic compounds. This work will review the main theories accounting for their assembly and for the origin and evolution of prokaryotic operons.
Keywords:Operon origin   Operon evolution   Metabolic pathway origin   Metabolic pathway evolution
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