Peripheral blood stem cell transplantation: approaches to an optimal blood stem cell collection |
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| Authors: | Coffe C Couteret Y Devillers M Fest T Morel P Pouthier-Stein F Calot J P Novakovitch G Sitthy X Tremisi P J |
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| Affiliation: | 1. Department of Agricultural Science, University of Bologna, viale Fanin 42, 40136 Bologna, Italy;2. Department of Biotechnology and Food Science, University of Burgos, Plaza Misael Bañuelos s/n, 09001 Burgos, Spain;3. Department of Microbiology, Biochemistry, Molecular Biology and Biotechnology, University of Maribor, Pivola 10, 2311 Hoce, Slovenia;4. Department of Life Science, University of Modena and Reggio Emilia, Via Campi 183, 41125 Modena, Italy;1. Department of Chemistry, University of Maine, 178 Munson Road, Orono, ME 04469, USA;2. School of Forest Resources, University of Maine, 5755 Nutting Hall, Orono, ME 04469, USA;3. Advanced Structures and Composites Center, University of Maine, 35 Flagstaff Road, Orono, ME 04468, USA |
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| Abstract: | ![]()
In 1992 peripheral blood stem cells (PBSCs) were widely used for autologous transplantation in a variety of malignancies, either alone or with autologous bone marrow transplantation. They have also been used in allogeneic transplantation. PBSCs may serve as an alternative, in some patients, to marrow hematopoietic stem cells (simple harvesting, less pain and discomfort, no general anesthesia, shorter time required for hematologic recovery after transplantation, accelerated restoration of immune function, …)In this article, we present a survey of peripheral blood stem cell collection approaching it from a very practical point of view (equipment, vascular access, stem cell collection) and we also show how to optimize PBSC collection procedures. Lastly, we envisage future developments. |
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