甲状腺乳头状癌病理组织学亚型及其临床意义

本文结合１９５４年－１９７８年间外科治疗甲状腺乳头状癌２６８例病理资料，参照癌组织结构和癌细胞的分化程度，将本癌分成Ⅰ型（分化较好型）、Ⅱ型（中间型）及Ⅲ型（分化较差型）３个亚型、临床观察，３型的临床表现各异，经外科治疗后，１０年以上无瘤生存率分别为９３．６％、６６．６％及２０％（Ｐ＜０．０１）基本符合Ⅰ、Ⅱ、Ⅲ型分别从较好到较差的逐级改变，对临床处理及判断预后有参考意义。

Histopathological Subtypes of Papillary Carcinoma of the Thyroid

Two hundred and sixty eight cases of papillary thyroid carcinoma treated with surgery during 1954-1976 were divided into three histological subtypes s fairly well differentiated type(140 cases,52. 2%),intermediate type (106 cases,39. 6%) ,and rather poor differentiated type(22 cases,8. 2%)based on various features of histologic structure and degree of differentiation of the tumor cells. Clinical observation revealed that clinical pictures of these types were distinctly different from type to type. The 10-year survival rates of patients in order of the above three subtypes were 93. 6 % ,66. 6% and 20% (P<0. 01) respectively.As a result ,it would be justified to regard the three types of lesions as histopathological entities of the papillary carcinoma of the thyroid.