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胃癌围手术期FM方案化疗的临床研究
引用本文:李汉贤 庄英帜. 胃癌围手术期FM方案化疗的临床研究[J]. 中国肿瘤临床, 1994, 21(8): 604-606
作者姓名:李汉贤 庄英帜
作者单位:衡阳医学院第一附属医院肿瘤外科!衡阳市421001(李汉贤,王阳北),衡阳医学院第一附属医院肿瘤内科!衡阳市421001(庄英帜)
摘    要:为探讨胃癌围手术期保驾化疗的可行性及临床意义,421例胃癌手术病人随机分成2组,试验组在围手术期施行FM方案化疗3周,另一组为对照组.结果显示胃癌病人能耐受围手术期化疗,两组对比围手术期化疗未增加术后并发症及危险性.试验组与对照组根治术后病人1、3、5年生存率分别为78.2%、51.2%、34.0%及64.7%,39.7%,24.8%(P<0.05).

关 键 词:胃癌  化疗  围手术期

Clinical Trial of Perioperative Chemotherapy Using FM Combination Protocol in Patient with Gastric Cancer
Li Han-Alan et al First Hospital,Hengyang Medical College,Hengyang. Clinical Trial of Perioperative Chemotherapy Using FM Combination Protocol in Patient with Gastric Cancer[J]. Chinese Journal of Clinical Oncology, 1994, 21(8): 604-606
Authors:Li Han-Alan et al First Hospital  Hengyang Medical College  Hengyang
Abstract:In order to evaluate the feasibility and clinical role of perioperative chemotherapy in patients with gastric cancer, a series of 421 cases who underwent gastrectomy were divided randomly into two groups. Patients in the trial group were given FM protocol chemotherapy during the perioperative period for 3 weeks. The results showed that the patients tolerated well the perioperative chemotherapy and no increase of postoperative complications nor jeopardy were experienced. The 1-,3-.5-year survival rates in the chemotherapy group were 78. 2% ,51. 2%,34. 0%and those in the control group were 64. 7%,39. 7%.24. 8%respective-ly(P<0. 05). There was a significant difference between the two groups.
Keywords:Stomach cancer Chemotherapy Perioperative
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