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Rosette formation by mouse lymphocytes. III. Receptors for immunoglobulin on normal and activated T cells
Authors:C. Soteriades-Vlachos  Maria I. C. Gy?ngy?ssy  J. H. L. Playfair
Abstract:By the use of an indirect immunofluorescent method for the identification of mouse T lymphocytes forming rosettes with antibody-coated erythrocytes, it was found that about 10% of the T cells in normal mouse spleen have receptors for antibody. Inhibition experiments with purified aggregated immunoglobulins showed that IgG2 is the major class involved. The same receptor was found on T cells activated against H-2 isoantigens. The importance of using the appropriate red cells and antiserum for demonstrating receptors on T cells is stressed.
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