D二聚体及FDP检测在骨折患者的应用价值

目的:探讨D二聚体(DD)及纤维蛋白(原)降解产物(FDP)定量检测在骨折病人的临床价值。方法:采用免疫比浊法对124例骨折患者术前、术后第2天及第7天进行血浆DD及FDP的定量检测,观察指标变化。结果:124例患者有15例并发深静脉栓塞(DVT),其中3例并发肺栓塞(PE),并发DVT组术前、术后血浆DD及FDP的检测结果有显著性差异(P<0.05),呈进行性增高。未并发DVT组术前、术后的检测结果无显著性差异(P>0.05)。而并发DVT组与未并发DVT组相比较,血浆DD及FDP的检测结果有显著性差异(P<0.05)。结论:血浆DD及FDP的动态监测对骨折术后并发血栓性疾病具有早期诊断价值。

Value of D-Dimer and FDP testing in patients with fracture

Objective: The aim of this study was to evaluate the measurement of plasma D-Dimer(DD) and fibrinogen degradation products(FDP) level in fracture.Methods: Automated latex immunoassay for the determination was used to detect plasma DD and FDP in 124 patients with fracture during the phases preoperative,2 days and 7 days postoperative.Results: 15 patients occur deep vein thrombosis(DVT),include 3 patients occur pulmonary embolism(PE).The different level of DD and FDP during the phases preoperative and postoperative in DVT group was significant(P<0.05).The different level of DD and FDP during the phases preoperative and postoperative in NO DVT group was not significant(P>0.05).The different level of DD and FDP between two groups was significant(P< 0.05).Conclusion: The determination of DD and FDP is very useful for predicting occurrence of thromboembolism in fracture.