中老年人群高尿酸血症与糖脂代谢紊乱及膳食因素的关系研究

目的 探讨中老年人群高尿酸血症和糖脂代谢紊乱及膳食因素之间的关系。 方法 随机抽取183例社区卫生服务中心体检人员及241例住院呼吸类疾病患者为调查对象，调查两组人群高尿酸血症、糖脂代谢紊乱的患病情况，并采用半定量食物频率问卷了解非住院组调查对象的膳食状况。 结果 ①两组人群中，男性高尿酸血症检出率均高于女性（P<0.01）。②男性、高血糖水平、高胆固醇血症、高甘油三酯血症，畜禽肉类、酒类、能量及脂类的过量摄入可能增加高尿酸血症的患病风险（P<0.05）；蔬果类的适量摄入可能降低高尿酸血症的患病风险（P<0.01）。结论 高尿酸血症与糖脂代谢紊乱及膳食因素关系密切。及早对高危人群进行糖脂代谢监测及膳食干预，对高尿酸血症防治有重要意义。

Dietary Factors Associated with Hyperuricemia and Glyeolipid Metabolism Disorder in Middle-aged and Elderly People

Objective To identify dietary factors associated with glyeolipid metabolism disorder and hyperuricemia in middle-aged and elderly people. Methods 183 visitors to a community health service center for physical examinations and 241 respiratory patients admitted to a hospital ward were randomly selected. The prevalence of hyperuricemia and dyslipidemic diabetics in the two groups of participants was investigated. Dietary information was collected using a semi-quantitative food frequency questionnaire. Results ① Male participants had a higher level of prevalence of hyperuricemia than female (P<0.01). ②Hypoglycemia, hypercholesterolemia, hypertriglyceridemia and excessive intake of meat, poultry, alcohol, energy and fat were risk factors of hyperuricemia (P<0.05); whereas, moderate intake of vegetables and fruits were protective factors (P<0.01）. Conclusion Hyperuricemia is associated with glyeolipid metabolism disorder and dietary factors. Early monitoring of glucose and lipid metabolism and dietary interventions in high risk population may play an important role in the prevention of hyperuricemia.