Regional assignment of the gene coding for human sucrase-isomaltase (SI) to chromosome 3q25-26 |
| |
| Authors: | L. F. WEST,M. B. DAVIS&dagger ,F. R. GREEN,R. H. LINDENBAUM&dagger ,D. M. SWALLOW |
| |
| Affiliation: | *MRC Human Biochemical Genetics Unit, The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE;†Charing Cross and Westminster Hospital Medical School, Page St. Wing, London SW1P 2AP;‡Department of Medical Genetics, Churchill Hospital, Oxford OX3 7LJ. |
| |
| Abstract: | The gene coding for sucrase-isomaltase ( SI ) has recently been mapped to chromosome 3 using a cDNA probe to analyse DNA from somatic cell hybrids (Green et al. 1987). We have now used this same cDNA probe to obtain a regional localization of this gene. In situ hybridization to normal metaphase chromosomes and to chromosomes from individuals with balanced translocations suggests a regional assignment to chromosome 3q25-26. |
| |
| Keywords: | |
|
|
