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| 精氨酸布洛芬滴眼液的制备及质量控制 | |
| 引用本文： | 李仲昆,靳梅,尹为民,王珩,王崇静,李冰. 精氨酸布洛芬滴眼液的制备及质量控制[J]. 中国药学杂志, 2004, 39(5): 362-363 |
| 作者姓名： | 李仲昆 靳梅 尹为民 王珩 王崇静 李冰 |
| 作者单位： | 1. 昆明市延安医院,云南,昆明,650051 2. 云南省第一人民医院,云南,昆明,650032 |
| 摘 要： | 目的 研制精氨酸布洛芬滴眼液以适应患者需求。方法 按处方配制成布洛芬浓度为3 mg·mL-1的精氨酸布洛芬滴眼液,采用紫外分光光度法测定其含量,建立其质量控制标准。结果 制备工艺可行,处方成分在272 nm处有最大吸收,其它成分在此波长处无吸收,质量控制可靠。结论 该剂型可以应用于临床。 |
| 关 键 词： | 精氨酸-布洛芬 滴眼液 质量控制 |
| 文章编号： | 1001-2494(2004)05-0362-02 |
| 收稿时间： | 2003-07-15; |
Preparation and quality control of arginine-ibuprofen eye drops |
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| LI Zhong-Kun,JIN Mei,YIN Wei-min,WANG Heng,WANG Chong-jing,LI Bing. Preparation and quality control of arginine-ibuprofen eye drops[J]. Chinese Pharmaceutical Journal, 2004, 39(5): 362-363 | |
| Authors: | LI Zhong-Kun JIN Mei YIN Wei-min WANG Heng WANG Chong-jing LI Bing |
| Affiliation: | 1.The Yan'an Hospital of Kunming,Kunming 650051,China;2.The First People Hospital of Yunnan,Kunming 650032,China |
| Abstract: | OBJECTIVE To prepare arginine-ibuprofen eye drops to meet the need of patients. METHODS Arginine-ibuprofen eye drops was prepared. The concentration of ibuprofen was 3 mg·mL-1.UV spectrophotometry was used to determine the content of ibuprofen. Quality control standard was established. RESULTS The process was practicable. Ibuprofen had maximum absorption at 272 nm. The other components had not absorption at this wavelength. The quality standard may be used to control the quality of this product. CONCLUSION It may be used in clinical. |
| Keywords: | arginine-ibuprofen eye drops quality control |
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